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1,3,5,7,8-Pentamethyl-2,6-dinitro-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene | CAS 131083-17-5
| Catalog Number | F01-0106 |
| Category | BODIPY |
| Molecular Formula | C14H15BF2N4O4 |
| Molecular Weight | 352.105 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres.
Product Specification
Application
| Excitation | 649 |
| Emission | 667 |
| Storage | Store at -20°C |
1,3,5,7,8-Pentamethyl-2,6-dinitro-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene, more commonly known as BODIPY 493/503, is a versatile fluorescent dye widely applied in scientific research.
Fluorescent Imaging: Within the realm of fluorescence microscopy, BODIPY dyes reign supreme. With their exceptional fluorescence quantum yield and photostability, these dyes yield vivid and crisp images, illuminating cellular structures and processes. Researchers leverage these dyes to delve into cellular compartments, track dynamic cellular behaviors, and visualize biomolecular interactions unfolding in real-time.
Bioassays and Diagnostics: Boasting superior chemical stability and customizable fluorescence properties, BODIPY compounds are the go-to choice for bioassays and diagnostics. These compounds serve as markers in immunoassays, enabling precise detection of target molecules. Their tunable wavelength properties enhance sensitivity and accuracy, making them indispensable for cutting-edge diagnostic tests.
Photodynamic Therapy: On the frontier of medical innovation, BODIPY derivatives are under scrutiny for their potential in photodynamic therapy (PDT), a groundbreaking treatment leveraging light-activated compounds to unleash reactive oxygen species and annihilate cancer cells. These dyes' absorption characteristics can be finely tailored for optimal light activation, positioning them as prime candidates for targeted cancer therapies. Researchers are delving into their efficacy and safety profiles in preclinical models, paving the way for groundbreaking therapeutic approaches.
Molecular Probes: Serving as molecular probes, BODIPY dyes offer insights into biochemical interactions and environmental fluctuations. Their fluorescence can be modulated by variables like pH, polarity, and molecular binding, rendering them invaluable tools for sensing environmental cues. Scientists harness these probes to monitor shifts in cellular metabolism and probe interactions among biomolecules, unraveling the intricate web of biological dynamics.
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