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WSP-5 | CAS 1593024-78-2
| Catalog Number | A16-0015 |
| Category | Other Cell Fluorescent Probes |
| Molecular Formula | C44H26N2O7S4 |
| Molecular Weight | 822.9 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
WSP-5 is a fluorescent probe for fast detection of H2S in biological samples and cells. WSP-5 selectively and rapidly reacts with H2S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy.
Chemical Information
Product Specification
Application
| Synonyms | 3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-(pyridin-2-yldisulfanyl)benzoate); Washington State Probe-5 |
| Purity | ≥95% |
| Canonical SMILES | C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)OC(=O)C5=CC=CC=C5SSC6=CC=CC=N6)OC7=C3C=CC(=C7)OC(=O)C8=CC=CC=C8SSC9=CC=CC=N9 |
| InChI | InChI=1S/C44H26N2O7S4/c47-41(30-12-2-5-15-37(30)54-56-39-17-7-9-23-45-39)50-27-19-21-33-35(25-27)52-36-26-28(20-22-34(36)44(33)32-14-4-1-11-29(32)43(49)53-44)51-42(48)31-13-3-6-16-38(31)55-57-40-18-8-10-24-46-40/h1-26H |
| InChIKey | DSMMZTASSIAQPQ-UHFFFAOYSA-N |
| Appearance | Solid Powder |
| Excitation | 502 nm |
| Emission | 525 nm |
| Storage | Store at -20°C |
WSP-5 is a sophisticated fluorescent probe specifically designed for the rapid detection of hydrogen sulfide (H2S) in biological samples and cells. This probe is highly selective for H2S, allowing it to differentiate this particular molecule from other biological components with remarkable precision. The uniqueness of WSP-5 lies in its mechanism, where it employs a reaction-based fluorescent turn-on strategy. Upon reacting with H2S, WSP-5 undergoes a chemical transformation that leads to an increase in its fluorescence, thereby signaling the presence of H2S. This makes WSP-5 a valuable tool for researchers looking to monitor H2S levels in various biological settings.
One of the critical applications of WSP-5 is in biomedical research, where it is used to study the role of hydrogen sulfide in physiological and pathological processes. Scientists utilize WSP-5 to elucidate how H2S functions as a signaling molecule, potentially influencing inflammation, vasodilation, and neuromodulation. By providing real-time insights into H2S dynamics, WSP-5 aids in understanding its contributions to various cellular processes and diseases.
Another significant application of WSP-5 is in pharmaceutical development. Researchers employ this probe to explore the therapeutic potential of H2S-donating drugs. Through the precise detection of H2S release within cellular environments, WSP-5 helps in evaluating the efficacy and safety of new therapeutic agents, supporting the development of drugs aimed at modulating H2S levels to treat a variety of diseases, including cardiovascular and neurodegenerative disorders.
In environmental and toxicological studies, WSP-5 serves as a crucial tool for detecting H2S in different settings. By monitoring H2S levels, researchers can assess environmental pollution and analyze the toxicological impacts of H2S exposure on living organisms. This is particularly important in industrial settings where H2S emissions need to be controlled and minimized to prevent harmful effects on human health and the environment.
Finally, WSP-5 is employed in agricultural research to study the role of H2S in plant biology. Researchers use this probe to investigate how H2S affects plant growth and stress responses. By enabling the detailed study of H2S within plant tissues, WSP-5 contributes to the development of strategies aimed at enhancing crop yield and resilience, thereby supporting food security and sustainable agricultural practices.
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