Tetramethylrhodamine methyl ester perchlorate

- Catelog Number: A16-0053
- Category: Mitochondrial Fluorescent Probes
Tetramethylrhodamine methyl ester (TMRM) perchlorate is a cell-permeant red fluorescent probe commonly used to monitor membrane potential of mitochondria using live cell fluorescence microscopy and flow cytometry. TMRM is a lipophilic cation accumulated by mitochondria and exhibits a red shift in the emission of 575 nm. However, when the membrane is depolarized, as in apoptosis, TMRM is not accumulated in the mitochondria. Thus, the strength of the fluorescence signal in mitochondria is used to assess cell viability.
Chemical Information | |
---|---|
Catelog Number: | A16-0053 |
Product Name: | Tetramethylrhodamine methyl ester perchlorate |
CAS Number: | 115532-50-8 |
Molecular Formula: | C25H25N2O3·ClO4 |
Molecular Weight: | 500.9 |
Purity: | ≥98% |
Synonyms: | TMRM Perchlorate; TMR methyl ester perchlorate; 3,6-bis(dimethylamino)-9-[2-(methoxycarbonyl)phenyl]-xanthylium perchlorate |
Product Specification | |
---|---|
Appearance: | Solid Powder |
Storage Conditions: | Store at -20°C |
Excitation Maximum (nm): | 515, 555 |
Emission Maximum (nm): | 575 |
Additional Information | |
---|---|
InChI: | InChI=1S/C25H25N2O3.ClHO4/c1-26(2)16-10-12-20-22(14-16)30-23-15-17(27(3)4)11-13-21(23)24(20)18-8-6-7-9-19(18)25(28)29-5;2-1(3,4)5/h6-15H,1-5H3;(H,2,3,4,5)/q+1;/p-1 |
InChIKey: | PFYWPQMAWCYNGW-UHFFFAOYSA-M |
CanonicalSMILES: | CN(C)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](C)C)C=C3O2)C4=CC=CC=C4C(=O)OC.[O-]Cl(=O)(=O)=O |
Online Inquiry
Related Products
0
Inquiry Basket