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Product Introduction
Yakima Yellow® CPG is a modified CPG solid support used in DNA synthesis. It allows for better attachment of DNA strands and higher yields with selectivity towards difficult sequences. This product is commonly used in the development of oligonucleotide therapeutics for various diseases such as cancers, viral infections, and genetic disorders.
Chemical Information
Product Specification
Application
Chemical Information
| Synonyms | Yakima Yellow® CPG 1000Å; Yakima Yellow CPG; 3-(5,6,4',7'-tetrachloro-5'-methyl-3',6'-dipivaloylfluorescein-2-yl)-propanamido-1-(2-O-dimethoxytrityloxymethyl)-pyrrolidin-4-yl-succinoyl long chain alkylamino-CPG |
Product Specification
| Storage | Store at -20°C |
Application
Yakima Yellow CPG is a commercially used pigment-grade organic dye material supplied in a click-chemistry reagent context, typically leveraged as a colorimetric and imaging-compatible labeling component in chemical biology and materials workflows. As a functional chromophore-containing building block, it is commonly incorporated into conjugation strategies where optical readout, surface or polymer integration, and robust signal generation are important. In downstream applications, Yakima Yellow CPG is selected for its compatibility with labeling pipelines that benefit from visible-wavelength tracking and stable incorporation into complex biomolecular or material systems.
1. Fluorescent Labeling Workflows
Yakima Yellow CPG is used as a bright, visible-color reporter in labeling workflows that require straightforward optical tracking of conjugate formation and handling. Researchers incorporate the dye into biomolecule conjugation pipelines to monitor reaction progress, optimize labeling conditions, and verify batch-to-batch consistency when downstream assays rely on colorimetric or fluorescence-compatible readouts. In molecular imaging and chemical biology tool development, the chromophore serves as a practical tag for tracking conjugates during purification, fractionation, and assay setup, including workflows that couple labeled probes to targeting ligands or affinity handles.
2. Polymer and Surface Conjugation
Yakima Yellow CPG is applied in biomaterials and surface functionalization contexts where stable dye incorporation into polymer matrices or functional coatings enables visual verification of modification and spatial mapping. Materials scientists use the dye to prepare colored or optically trackable surfaces for studying adsorption, binding, and surface reactivity in controlled environments. The chromophore’s presence supports routine characterization of modified substrates by optical inspection and spectroscopy, which is valuable during iterative development of functional materials such as labeled hydrogels, coatings, and dye-containing polymer constructs.
3. Diagnostic Reagent Development
Yakima Yellow CPG is commonly incorporated into diagnostic reagent development and assay prototyping where a strong optical signal improves assay readability and workflow robustness. In research and industrial settings, the dye is used to generate colored conjugates or labeled components that can be integrated into test formats requiring clear visual contrast, including reagent components used for assay optimization and platform prototyping. Its role is typically centered on signal generation and readout compatibility, supporting the development of reagent systems where optical output is a primary design criterion.
4. Molecular Imaging Probes
Yakima Yellow CPG is used as an imaging-compatible labeling component in molecular imaging probe development, particularly in applications that benefit from visible-wavelength contrast and convenient detection. Chemical biology teams employ the dye to create optically trackable conjugates that can be followed during probe assembly, purification, and experimental setup. The chromophore label is also used to support multiplexing or orthogonal readout strategies in complex experimental designs where distinct optical channels help differentiate probe populations and conjugate states.
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