t-Boc-N-amido-PEG2-azide | 950683-55-3

Name: t-Boc-N-amido-PEG2-azide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R14-0163
Category	Azides
Molecular Formula	C11H22N4O4
Molecular Weight	274.30

Catalog Number	Size	Price	Quantity
R14-0163	--	$--

INQUIRY

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Worldwide Delivery
Quality Assurance
24/7 Customer Service

Product Introduction

Boc-N-Amido-PEG2-C2-azide is a polyethylene glycol (PEG)-based PROTAC linker. Boc-N-Amido-PEG2-C2-azide can be used in the synthesis of a series of PROTACs.

Chemical Information
Product Specification

Synonyms	tert-butyl {2-[2-(2-azidoethoxy)ethoxy]ethyl}carbamate; Boc-NH-PEG(2)-N3
Purity	≥ 98% (HPLC)
IUPAC Name	tert-butyl N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]carbamate
Canonical SMILES	CC(C)(C)OC(=O)NCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C11H22N4O4/c1-11(2,3)19-10(16)13-4-6-17-8-9-18-7-5-14-15-12/h4-9H2,1-3H3,(H,13,16)
InChI Key	MEZSEFQCLYODJG-UHFFFAOYSA-N
Appearance	Light yellow oil

Storage

Store at 2-8 °C

Computed Properties
XLogP3	1.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	11
Exact Mass	274.16410520 g/mol
Monoisotopic Mass	274.16410520 g/mol
Topological Polar Surface Area	71.2Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	298
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Patents

Publication Number	Title	Priority Date
JP-2023500377-A	Radiolabeled targeting ligand	2019-11-08
US-2019192668-A1	Irak degraders and uses thereof	2017-12-26
WO-2019133531-A1	Irak degraders and uses thereof	2017-12-26
AU-2018396142-A1	IRAK degraders and uses thereof	2017-12-26
US-10874743-B2	IRAK degraders and uses thereof	2017-12-26