t-Boc-N-amido-PEG2-azide

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t-Boc-N-amido-PEG2-azide

t-Boc-N-amido-PEG2-azide | CAS 950683-55-3

Catalog Number R14-0163
Category Azides
Molecular Formula C11H22N4O4
Molecular Weight 274.30
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Product Introduction

t-Boc-N-amido-PEG2-azide is a bifunctional polyethylene glycol linker featuring a tert-butyloxycarbonyl-protected amide and an azide terminus. Its amphiphilic structure facilitates solubility and compatibility in organic and aqueous media, making it ideal for conjugation strategies. The azide group enables selective biorthogonal click chemistry, commonly used for site-specific labeling and protein modification. This versatile reagent supports advancements in peptide synthesis, drug delivery research, and bioconjugation studies.

  • Chemical Information

  • Product Specification

  • Computed Properties

  • Patents

Synonyms tert-butyl {2-[2-(2-azidoethoxy)ethoxy]ethyl}carbamate; Boc-NH-PEG(2)-N3
Purity ≥ 98% (HPLC)
IUPAC Name tert-butyl N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]carbamate
Canonical SMILES CC(C)(C)OC(=O)NCCOCCOCCN=[N+]=[N-]
InChI InChI=1S/C11H22N4O4/c1-11(2,3)19-10(16)13-4-6-17-8-9-18-7-5-14-15-12/h4-9H2,1-3H3,(H,13,16)
InChIKey MEZSEFQCLYODJG-UHFFFAOYSA-N
Appearance Light yellow oil
Storage Store at 2-8 °C
XLogP3 1.5
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 11
Exact Mass 274.16410520 g/mol
Monoisotopic Mass 274.16410520 g/mol
Topological Polar Surface Area 71.2Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 298
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Publication Number Title Priority Date
JP-2023500377-A Radiolabeled targeting ligand 2019-11-08
US-2019192668-A1 Irak degraders and uses thereof 2017-12-26
WO-2019133531-A1 Irak degraders and uses thereof 2017-12-26
AU-2018396142-A1 IRAK degraders and uses thereof 2017-12-26
US-10874743-B2 IRAK degraders and uses thereof 2017-12-26

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