Pomalidomide-PEG5-Azide

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Pomalidomide-PEG5-Azide

Pomalidomide-PEG5-Azide

Catalog Number R14-0148
Category Azides
Molecular Formula C26H34N6O10
Molecular Weight 590.6
Catalog Number Size Price Quantity
R14-0148 -- $--

Product Introduction

Pomalidomide-PEG5-Azide, I is a PROTAC linker that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.Azide enable click chemistry with Alkyne, DBCO or BCN molecules.

Chemical Information

Purity 98%
IUPAC Name 3-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]propanamide
Canonical SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NC(=O)CCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI InChI=1S/C26H34N6O10/c27-31-28-7-9-39-11-13-41-15-17-42-16-14-40-12-10-38-8-6-22(34)29-19-3-1-2-18-23(19)26(37)32(25(18)36)20-4-5-21(33)30-24(20)35/h1-3,20H,4-17H2,(H,29,34)(H,30,33,35)
InChI Key TZOHJKYEXIATGQ-UHFFFAOYSA-N
  • Product Specification
Storage -20 °C

Computed Properties

XLogP3 0
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 12
Rotatable Bond Count 20
Exact Mass 590.23364130 g/mol
Monoisotopic Mass 590.23364130 g/mol
Topological Polar Surface Area 173Ų
Heavy Atom Count 42
Formal Charge 0
Complexity 991
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
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