NHS-Ac-N3

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NHS-Ac-N3

NHS-Ac-N3 | CAS 824426-32-6

Catalog Number R14-0325
Category Azides
Molecular Formula C6H6N4O4
Molecular Weight 198.13
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Product Introduction

NHS-Ac-N3 is a bioorthogonal conjugation building block that provides a bioorthogonal click handle for modular click-chemistry workflows. The molecule can be used to introduce a click-reactive group onto an antibody, peptide, linker intermediate, or payload-containing component, depending on the chemistry of its second terminal functionality. Its additional reactive group is not clearly defined from product name; verify structure before assigning antibody conjugation chemistry. Conjugation can be performed using spaac with dbco/bcn-functionalized partner or cuaac with terminal alkyne partner, depending the complementary handle. The sequence and orientation of the coupling steps should be selected according to the functional groups carried by the two conjugation partners.

  • Chemical Information

  • Product Specification

  • Application

  • QC Data

Chemical Information

Synonyms Azidoacetic acid NHS ester;(2,5-Dioxopyrrolidin-1-yl) 2-azidoacetate;
Purity ≥98%
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 2-azidoacetate
SMILES C1CC(=O)N(C1=O)OC(=O)CN=[N+]=[N-]
InChI InChI=1S/C6H6N4O4/c7-9-8-3-6(13)14-10-4(11)1-2-5(10)12/h1-3H2
InChIKey FENNDBOWHRZLTQ-UHFFFAOYSA-N
Appearance White crystalline powder

Product Specification

Storage Store at-20 °C

Application

QC Data

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