NBD Sphingosine | 1449370-25-5

Catalog Number	A16-0055
Category	Lipid Fluorescent Probes
Molecular Formula	C24H39N5O5
Molecular Weight	477.60

Catalog Number	Size	Price	Quantity
A16-0055	--	$--

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Product Introduction

NBD sphingosine is a sphingosine derivative that is tagged with a fluorescent group nitrobenzoxadiazole (NBD). It has been used to study the cellular localization and metabolism of sphingosine in HeLa cells. NBD sphingosine also inhibits proliferation of HCT116, PC3, HEK293T, and HFE-145 cells (IC50 = 25.6, 40.5, 10.4, and 12.5 μM, respectively).

Chemical Information
Related CAS	799268-47-6
Synonyms	omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol; D-erythro-Sphingosine-N-NBD
Purity	≥95%
IUPAC Name	2-amino-18-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]octadec-4-ene-1,3-diol
Canonical SMILES	C1=C(C2=NON=C2C(=C1)[N+](=O)[O-])NCCCCCCCCCCCCCC=CC(C(CO)N)O
InChI	InChI=1S/C24H39N5O5/c25-19(18-30)22(31)14-12-10-8-6-4-2-1-3-5-7-9-11-13-17-26-20-15-16-21(29(32)33)24-23(20)27-34-28-24/h12,14-16,19,22,26,30-31H,1-11,13,17-18,25H2/b14-12+/t19-,22+/m0/s1
InChI Key	MNFOPKRTMFDMJV-HCEDEFRUSA-N
Density	1.2±0.1 g/cm3
Boiling Point	674.7±65.0 °C at 760 mmHg

Product Specification

Storage

Store at -20°C

Computed Properties
XLogP3	5.1
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	18
Exact Mass	477.29511936 g/mol
Monoisotopic Mass	477.29511936 g/mol
Topological Polar Surface Area	163Å²
Heavy Atom Count	34
Formal Charge	0
Complexity	576
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes