N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) | CAS 2353409-46-6

Name: N-(t-butyl ester-PEG2)-N-bis(PEG3-azide)
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R14-0051
Category	Azides
Molecular Formula	C28H53N7O11
Molecular Weight	663.8

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Product Introduction

N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) is a branched conjugation reagent The azide groups is very reactive with alkyne such as DBCO, BCN and propargyl reagnet via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases the hydrophilic properties of the compound.

Chemical Information
Product Specification
Application

Purity	98%
Solubility	DMSO, DCM, DMF

Storage

-20 °C

N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) is a compound with diverse applications in bio-conjugation and drug delivery systems. Here are four key applications:

Targeted Drug Delivery: Positioned at the forefront of targeted drug delivery, N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) plays a pivotal role in shaping sophisticated drug delivery systems. By fusing therapeutic agents with this compound, researchers can optimize drug solubility and stability while directing them precisely towards specific cells or tissues. This precision-driven method elevates treatment efficacy and accuracy while simultaneously minimizing unwanted side effects.

Bio-conjugation: Delving into the realm of bio-conjugation, the utilization of N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) streamlines the bonding of biomolecules, such as proteins and peptides, to various surfaces or other biomolecules. The azide functional groups within this compound serve as receptive sites for click chemistry reactions, paving the way for stable and selective conjugation. This application holds considerable significance in advancing biosensors, imaging agents, and therapeutic proteins – expanding avenues for innovation in biotechnology.

Biomedical Imaging: Navigating the intricate landscape of biomedical imaging, N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) emerges as a key player in the development of contrast agents for imaging modalities like MRI and PET scans. By linking imaging agents to this compound, researchers enhance visibility and specificity within biological tissues, fostering superior disease diagnosis and progression monitoring. This cutting-edge innovation promises heightened precision and efficacy in the realm of medical imaging technology.

Polymer Synthesis: Unveiling its versatility in polymer science, N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) acts as a foundational building block for crafting complex polymer architectures with tailored properties. Leveraging its dual-functional attributes, this compound enables the incorporation of diverse functional groups into polymer chains, facilitating the design of materials with specific traits like hydrophilicity, biocompatibility, and controlled degradation kinetics. This application underscores the boundless potential of N-(t-butyl ester-PEG2)-N-bis(PEG3-azide) in driving innovation and flexibility in polymer science.