N-(Azido-PEG2)-N-Biotin-PEG3-acid | CAS 2112731-59-4

Name: N-(Azido-PEG2)-N-Biotin-PEG3-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	R14-0079
Category	Azides
Molecular Formula	C25H44N6O9S
Molecular Weight	604.7

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Product Introduction

N-(Azido-PEG2)-N-Biotin-PEG3-acid is aclick chemistry biotinylation reagent. The azide group enables Click Chemistry. The terminal carboxylic acid can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Chemical Information
Product Specification
Application

Purity

98%

Storage

-20 °C

N-(Azido-PEG2)-N-Biotin-PEG3-acid, a versatile compound with a plethora of applications in biochemical research and biotechnology. Here are four key applications:

Bioconjugation: An indispensable tool in bioconjugation techniques, N-(Azido-PEG2)-N-Biotin-PEG3-acid plays a pivotal role in attaching biomolecules to surfaces or probes. The azide functionality sparks click chemistry reactions, facilitating precise and efficient linkage of biotinylated molecules to diverse entities. This application is paramount in crafting top-tier biosensors and diagnostic tools that push the boundaries of technological innovation.

Protein Labeling: A steadfast reagent for biotinylating proteins, this compound enables their detection, purification, and immobilization for a myriad of applications. Biotinylated proteins can firmly bind to streptavidin or avidin-coated surfaces, showcasing high-affinity interactions. In assays like Western blotting, ELISA, and immunoprecipitation, where precise protein detection is non-negotiable, this compound shines as a beacon of accuracy and reliability.

Drug Delivery: Unlocking the potential for targeted drug delivery systems, N-(Azido-PEG2)-N-Biotin-PEG3-acid conjugates therapeutic agents to biotinylated carriers, ushering in a new era of precision medicine. The biotin-streptavidin interaction acts as a beacon, guiding drugs to specific cells or tissues. This strategic approach enhances treatment efficacy while safeguarding against off-target effects and minimizing toxicity, setting a new standard for therapeutic delivery mechanisms.

Cell Imaging: A key player in cellular imaging techniques, this compound is employed to label cells with fluorescent or other detectable tags, revolutionizing the field of cellular visualization. By attaching a fluorescent molecule to the biotinylated compound, researchers can track cell movement and localization in vitro or in vivo with unparalleled precision.