N-(Acid-PEG2)-N-bis(PEG3-azide) | 2320560-35-6

N-(Acid-PEG2)-N-bis(PEG3-azide) is a polyethylene glycol derivative widely utilized in bioconjugation and molecular biology. Let’s explore four key applications of this compound:

Bioconjugation: Embedded in the core of bioconjugation processes, N-(Acid-PEG2)-N-bis(PEG3-azide) emerges as a versatile tool for connecting biomolecules like proteins and antibodies to a myriad of molecules and surfaces. Its azide groups serve as catalysts for click chemistry reactions with alkyne-functionalized counterparts, fostering precise and enduring conjugations, pivotal for the progression of targeted drug delivery systems and diagnostic tools, propelling the forefront of groundbreaking biomedical research.

Nanotechnology: Venturing into the realm of nanotechnology, N-(Acid-PEG2)-N-bis(PEG3-azide) plays a crucial role in tailoring the surface characteristics of nanoparticles. By binding to nanoparticles, it enhances solubility and biocompatibility, extending their circulation in the bloodstream.

Drug Delivery: Leveraging the unique properties of N-(Acid-PEG2)-N-bis(PEG3-azide), researchers can craft intelligent drug delivery systems with finesse. The inherent PEG chains offer stealth properties, mitigating immunogenic responses and prolonging circulation duration. Through sophisticated functionalization, it enables the attachment of targeting ligands, facilitating precise drug delivery to specific afflicted cells, such as cancer cells.

Material Science: Within the dynamic landscape of material science, N-(Acid-PEG2)-N-bis(PEG3-azide) plays a critical role in functionalizing polymer surfaces and hydrogels. This compound confers antifouling attributes and enhances interaction between materials and biological tissues. Such enhancements are crucial in the development of cutting-edge medical implants, tissue engineering scaffolds, and biosensors, underscoring the interdisciplinary synergy of material science in catalyzing breakthroughs in healthcare and beyond.