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N-(1-Pyrenyl)maleimide | 42189-56-0
| Catelog Number | F08-0015 |
| Category | Pyrene |
| Molecular Formula | C20H11NO2 |
| Molecular Weight | 297.31 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| F08-0015 | -- | $-- |
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Product Introduction
N-(1-Pyrenyl)maleimide is a thiol-reactive fluorescent probe.
Chemical Information |
|
|---|---|
| Synonyms | 1-pyren-1-ylpyrrole-2,5-dione |
| Purity | > 97.0 % (HPLC) |
| IUPAC Name | 1-pyren-1-ylpyrrole-2,5-dione |
| Canonical SMILES | C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)N5C(=O)C=CC5=O |
| InChI | InChI=1S/C20H11NO2/c22-17-10-11-18(23)21(17)16-9-7-14-5-4-12-2-1-3-13-6-8-15(16)20(14)19(12)13/h1-11H |
| InChI Key | YXKWRQLPBHVBRP-UHFFFAOYSA-N |
| Density | 1.2310 (rou gh estimate) |
| Appearance | Yellow solid |
| Refractive Index | 1.5180 (estimate) |
| Boiling Point | 438.82 ℃ (rough estimate) |
| Melting Point | >228 ℃ (dec.) |
| MDL Number | MFCD00049301 |
| LogP | 4.07840 |
Product Specification |
|
|---|---|
| Condition To Avoid | Light Sensitive |
| Storage | Refrigerator |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | 4.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 297.078978594 g/mol |
| Monoisotopic Mass | 297.078978594 g/mol |
| Topological Polar Surface Area | 37.4Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 550 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22707200 | 2012-09-01 | N-(1-Pyrenyl) maleimide inhibits telomerase activity in a cell free system and induces apoptosis in Jurkat cells | Molecular biology reports |
| 22779734 | 2012-08-07 | The extent of pyrene excimer fluorescence emission is a reflector of distance and flexibility: analysis of the segment linking the LDL receptor-binding and tetramerization domains of apolipoprotein E3 | Biochemistry |
| 22730894 | 2012-07-17 | Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4 | Biochemistry |
| 23016296 | 2012-06-01 | [Determination of homocysteine in plasma by precolumn derivatization-high performance liquid chromatography with fluorescence detection] | Se pu = Chinese journal of chromatography |
| 21321387 | 2011-03-07 | High-energy radiation monitoring based on radio-fluorogenic co-polymerization II: fixed fluorescent images of collimated x-ray beams using an RFCP gel | Physics in medicine and biology |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| JP-2022136141-A | Coloring composition for color filter and color filter | 2022-07-20 |
| JP-2022040133-A | A photosensitive coloring composition for a color filter for a solid-state image sensor, a color filter, and a solid-state image sensor using the same. | 2021-12-15 |
| JP-2022008395-A | Red coloring composition for organic EL display device, color filter for organic EL display device and organic EL display device | 2021-09-14 |
| JP-7050207-B1 | Organic EL display device | 2021-04-22 |
| WO-2022224779-A1 | Organic el display device | 2021-04-22 |
Applications of Fluorescent Probes & Dyes
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