1-Pyrenebutyric Acid

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1-Pyrenebutyric Acid

1-Pyrenebutyric Acid | 3443-45-6

Catelog Number F08-0011
Category Pyrene
Molecular Formula C20H16O2
Molecular Weight 288.34
Catalog Number Size Price Quantity
F08-0011 -- $--

Product Introduction

1-Pyrenebutanoic acid is a fluorescent probe that can be used to study proteins, lipids, nucleic acids and other biological systems.

Chemical Information

Synonyms Pyrenebutyric acid;4-(1-pyrenyl)butanoic acid; 4-pyren-1-ylbutanoic acid
Purity NMR 1H, HPLC-MS (95%)
IUPAC Name 4-pyren-1-ylbutanoic acid
Canonical SMILES C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CCCC(=O)O
InChI InChI=1S/C20H16O2/c21-18(22)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6H2,(H,21,22)
InChI Key QXYRRCOJHNZVDJ-UHFFFAOYSA-N
Solubility Good in DCM, chloroform
Density 1.296 g/cm3
Appearance Brownish yellow solid
Boiling Point 186-188 ℃
Melting Point 189 °C
MDL Number MFCD00004141
LogP 4.99130

Product Specification

Excitation 343; 326; 313; 276; 265; 242; 234
Emission 377; 397
Storage Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
Application Fluorescent probe.
Signal Warning
GHS Hazard Statements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Computed Properties

XLogP3 5.1
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 4
Exact Mass 288.115029749 g/mol
Monoisotopic Mass 288.115029749 g/mol
Topological Polar Surface Area 37.3Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 418
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMIDPublication DateTitleJournal
22743600 2012-09-01 Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery Biomaterials
23035414 2012-09-01 Hybrid low resistance ultracapacitor electrodes based on 1-pyrenebutyric acid functionalized centimeter-scale graphene sheets Journal of nanoscience and nanotechnology
22793649 2012-08-28 RGD-peptide functionalized graphene biomimetic live-cell sensor for real-time detection of nitric oxide molecules ACS nano
22765230 2012-07-31 Self-assembly of a diblock copolymer with pendant disulfide bonds and chromophore groups: a new platform for fast release Langmuir : the ACS journal of surfaces and colloids
22465335 2012-06-01 A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei Biomaterials

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