1-Pyrenebutyric Acid

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1-Pyrenebutyric Acid

1-Pyrenebutyric Acid | CAS 3443-45-6

Catalog Number F08-0011
Category Pyrene Dyes
Molecular Formula C20H16O2
Molecular Weight 288.34
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Product Introduction

1-Pyrenebutyric Acid is a fluorescent dye that features a pyrene chromophore, known for its extended conjugated aromatic system, which facilitates strong fluorescence emission in the blue region of the spectrum. This compound exhibits solvatochromic behavior, allowing its fluorescence properties to vary with environmental polarity, making it suitable for probing microenvironments in biochemical systems. Commonly used in fluorescence microscopy and biosensing applications, 1-Pyrenebutyric Acid can be incorporated into biomolecules through its carboxylic acid functionality, enabling the labeling of proteins and other macromolecules for detailed cellular imaging studies.

  • Chemical Information

  • Product Specification

  • Application

  • Computed Properties

  • Literatures

  • Patents

Chemical Information

Synonyms Pyrenebutyric acid;4-(1-pyrenyl)butanoic acid; 4-pyren-1-ylbutanoic acid
Purity NMR 1H, HPLC-MS (95%)
IUPAC Name 4-pyren-1-ylbutanoic acid
SMILES C1=CC2=C3C(=C1)C=CC4=C(C=CC(=C43)C=C2)CCCC(=O)O
InChI InChI=1S/C20H16O2/c21-18(22)6-2-3-13-7-8-16-10-9-14-4-1-5-15-11-12-17(13)20(16)19(14)15/h1,4-5,7-12H,2-3,6H2,(H,21,22)
InChIKey QXYRRCOJHNZVDJ-UHFFFAOYSA-N
Solubility Good in DCM, chloroform
Density 1.296 g/cm3
Appearance Brownish yellow solid
Boiling Point 186-188 °C
Melting Point 189 °C
MDL Number MFCD00004141
LogP 4.99130

Product Specification

Excitation 343; 326; 313; 276; 265; 242; 234
Emission 377; 397
Storage Storage: 24 months after receival at -20 °C in the Dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
Signal Warning
GHSHazardStatements H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Application

Computed Properties

XLogP3 5.1
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 4
Exact Mass 288.115029749 g/mol
Monoisotopic Mass 288.115029749 g/mol
Topological Polar Surface Area 37.3Ų
Heavy Atom Count 22
Formal Charge 0
Complexity 418
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Literatures

PMID Publication Date Title Journal
22743600 2012-09-01 Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery Biomaterials
23035414 2012-09-01 Hybrid low resistance ultracapacitor electrodes based on 1-pyrenebutyric acid functionalized centimeter-scale graphene sheets Journal of nanoscience and nanotechnology
22793649 2012-08-28 RGD-peptide functionalized graphene biomimetic live-cell sensor for real-time detection of nitric oxide molecules ACS nano
22765230 2012-07-31 Self-assembly of a diblock copolymer with pendant disulfide bonds and chromophore groups: a new platform for fast release Langmuir : the ACS journal of surfaces and colloids
22465335 2012-06-01 A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei Biomaterials

Patents

Publication Number Title Priority Date
CN-115132404-A A kind of manufacturing method of transparent flexible thin film electrode 2022-07-28
CN-115112738-A Preparation of a laser direct writing graphene/enzyme electrode and its application in glucose sensing 2022-07-21
CN-115028732-A Anti-benzo[a]pyrene monoclonal antibody and its application 2022-07-11
CN-115028733-A Monoclonal antibody and enzyme-linked immunosorbent assay and kit for the detection of pyrene and benzo[a]pyrene 2022-07-11
CN-114920203-A A kind of method that utilizes riboflavin compounds to produce hydrogen peroxide 2022-05-20

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