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MHI-148 | 172971-76-5
| Catalog Number | A16-0191 |
| Category | Lysosomal Fluorescent Probes |
| Molecular Formula | C42H52BrClN2O4 |
| Molecular Weight | 764.2 |
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Product Introduction
MHI-148 is a near-infrared heptamethine cyanine dye that possesses tumor-targeting properties. MHI-148 can be used as a promising tumor-targeting candidate and conjugated it with the anticancer drug PTX for successfully synthesizing PTX-MHI-148 conjugates (PTX-MHI).
Chemical Information |
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| Synonyms | MHI 148; MHI148; IR808; 1-(5-Carboxypentyl)-2-(2-(3-(2-(1-(5-carboxypentyl)-3,3-dimethylindolin-2-ylidene)ethylidene)-2-chlorocyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-3H-indol-1-ium bromide |
| Purity | 98% by HPLC |
| IUPAC Name | 6-[(2E)-2-[(2E)-2-[3-[(E)-2-[1-(5-carboxypentyl)-3,3-dimethylindol-1-ium-2-yl]ethenyl]-2-chlorocyclohex-2-en-1-ylidene]ethylidene]-3,3-dimethylindol-1-yl]hexanoic acid;bromide |
| Canonical SMILES | CC1(C2=CC=CC=C2[N+](=C1C=CC3=C(C(=CC=C4C(C5=CC=CC=C5N4CCCCCC(=O)O)(C)C)CCC3)Cl)CCCCCC(=O)O)C.[Br-] |
| InChI | InChI=1S/C42H51ClN2O4.BrH/c1-41(2)32-18-9-11-20-34(32)44(28-13-5-7-22-38(46)47)36(41)26-24-30-16-15-17-31(40(30)43)25-27-37-42(3,4)33-19-10-12-21-35(33)45(37)29-14-6-8-23-39(48)49;/h9-12,18-21,24-27H,5-8,13-17,22-23,28-29H2,1-4H3,(H-,46,47,48,49);1H |
| InChI Key | SBSLCJXMLMGYFH-UHFFFAOYSA-N |
Applications of Fluorescent Probes & Dyes
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