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PFB-FDGlu
| Catalog Number | A16-0137 |
| Category | Lysosomal Fluorescent Probes |
| Molecular Formula | C39H32F5NO16 |
| Molecular Weight | 865.67 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0137 | -- | $-- |
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Product Introduction
PFB-FDGlu is a green-fluorescent dye used for staining endosomal and lysosomal compartments.
Chemical Information |
|
|---|---|
| Synonyms | 5-(Pentafluorobenzoylamino)Fluorescein Di-β-D-Glucopyranoside |
| IUPAC Name | 2,3,4,5,6-pentafluoro-N-[3-oxo-3',6'-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]spiro[2-benzofuran-1,9'-xanthene]-5-yl]benzamide |
| Canonical SMILES | C1=CC2=C(C=C1NC(=O)C3=C(C(=C(C(=C3F)F)F)F)F)C(=O)OC24C5=C(C=C(C=C5)OC6C(C(C(C(O6)CO)O)O)O)OC7=C4C=CC(=C7)OC8C(C(C(C(O8)CO)O)O)O |
| InChI | InChI=1S/C39H32F5NO16/c40-24-23(25(41)27(43)28(44)26(24)42)35(54)45-12-1-4-16-15(7-12)36(55)61-39(16)17-5-2-13(56-37-33(52)31(50)29(48)21(10-46)59-37)8-19(17)58-20-9-14(3-6-18(20)39)57-38-34(53)32(51)30(49)22(11-47)60-38/h1-9,21-22,29-34,37-38,46-53H,10-11H2,(H,45,54)/t21-,22-,29-,30-,31+,32+,33-,34-,37-,38-/m1/s1 |
| InChI Key | YYMJMZGTQFITLS-WXKYVOLFSA-N |
| Appearance | Solid Powder |
Computed Properties | |
|---|---|
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 9 |
| Hydrogen Bond Acceptor Count | 21 |
| Rotatable Bond Count | 8 |
| Exact Mass | 865.16412474 g/mol |
| Monoisotopic Mass | 865.16412474 g/mol |
| Topological Polar Surface Area | 263Ų |
| Heavy Atom Count | 61 |
| Formal Charge | 0 |
| Complexity | 1500 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-10286038-B2 | Lysosome membrane protein 2 (LIMP-2) based peptides and related uses | 2016-03-11 |
| US-2017258870-A1 | Limp-2 based peptides and related uses | 2016-03-11 |
| EP-2504332-B1 | An amorphous and a crystalline form of genz 112638 hemitartrate as inhibitor of glucosylceramide synthase | 2009-11-27 |
| EP-2796457-A1 | Genz 112638 for treating Gaucher or Fabry disease in combination therapy | 2009-11-27 |
| EP-2796457-B1 | Genz 112638 for treating Gaucher or Fabry disease in combination therapy | 2009-11-27 |
Applications of Fluorescent Probes & Dyes
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