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Fluorescein diacetate | 596-09-8
| Catelog Number | F04-0038 |
| Category | Fluorescein FAM |
| Molecular Formula | C24H16O7 |
| Molecular Weight | 416.38 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| F04-0038 | -- | $-- |
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Product Introduction
Fluorescein diacetate is a vital dye widely used in the biomedical industry. It is primarily employed to assess the integrity of cell membranes and determine cell viability. By being hydrolyzed within living cells, this compound is converted to green fluorescent fluorescein. It finds applications in drug efficacy evaluation, studying disease progression, and cell sorting techniques.
Chemical Information |
|
|---|---|
| Synonyms | 3,6-Diacetoxyfluoran; Di-O-acetylfluorescein |
| Purity | >98.0%(HPLC) |
| IUPAC Name | (6'-acetyloxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-3'-yl) acetate |
| Canonical SMILES | CC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)C)C5=CC=CC=C5C(=O)O3 |
| InChI | InChI=1S/C24H16O7/c1-13(25)28-15-7-9-19-21(11-15)30-22-12-16(29-14(2)26)8-10-20(22)24(19)18-6-4-3-5-17(18)23(27)31-24/h3-12H,1-2H3 |
| InChI Key | CHADEQDQBURGHL-UHFFFAOYSA-N |
| Appearance | Solid |
| Melting Point | 206 °C |
| MDL Number | MFCD00005062 |
Product Specification |
|
|---|---|
| Condition To Avoid | Air Sensitive |
| Store Under Inert Gas | Store under inert gas |
| GHS Hazard Statements | Not Classified Reported as not meeting GHS hazard criteria by 2 of 2 companies. For more detailed information, please visit ECHA C&L website. |
Computed Properties | |
|---|---|
| XLogP3 | 3.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 416.08960285 g/mol |
| Monoisotopic Mass | 416.08960285 g/mol |
| Topological Polar Surface Area | 88.1Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 708 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 27633002 | 2016-11-01 | Enalapril protects against myocardial ischemia/reperfusion injury in a swine model of cardiac arrest and resuscitation | International journal of molecular medicine |
| 22661061 | 2012-11-01 | Deciphering the metabolic capabilities of a lipase producing Pseudomonas aeruginosa SL-72 strain | Folia microbiologica |
| 22704207 | 2012-11-01 | Chlorination-induced cellular damage and recovery in marine microalga, Chlorella salina | Chemosphere |
| 22960224 | 2012-11-01 | Impacts of florfenicol on marine diatom Skeletonema costatum through photosynthesis inhibition and oxidative damages | Plant physiology and biochemistry : PPB |
| 22568927 | 2012-10-01 | Effects of vitrification cryoprotectant treatment and cooling method on the viability and development of buffalo oocytes after intracytoplasmic sperm injection | Cryobiology |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115058344-A | Decoy microrobot for removing SARS-CoV-2 and its variants in wastewater, its preparation method and application | 2022-08-05 |
| CN-115058344-B | Decoy microrobots for removing SARS-CoV-2 and its mutant strains in wastewater, its preparation method and application | 2022-08-05 |
| CN-115201302-A | Electrochemical sensor, preparation method and application thereof | 2022-07-04 |
| US-11548891-B1 | Quaternary ammonium salts of phenanthroindolizidine and phenanthroquinolizidine alkaloids as hypoxia-targeted anticancer agents | 2022-04-22 |
| CN-114848579-A | leech vibrio-containing composition | 2022-04-06 |
Applications of Fluorescent Probes & Dyes
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