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Azido-PEG3-maleimide | 1858264-36-4
| Catalog Number | R14-0246 |
| Category | Azides |
| Molecular Formula | C15H23N5O6 |
| Molecular Weight | 369.37 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0246 | -- | $-- |
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Product Introduction
Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG3-maleimide is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Information |
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|---|---|
| Synonyms | Azido-PEG3-Maleimide Kit;N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide |
| Purity | >98.0% |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| IUPAC Name | N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide |
| Canonical SMILES | C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCOCCN=[N+]=[N-] |
| InChI | InChI=1S/C15H23N5O6/c16-19-18-5-8-25-10-12-26-11-9-24-7-4-17-13(21)3-6-20-14(22)1-2-15(20)23/h1-2H,3-12H2,(H,17,21) |
| InChI Key | OGSSEPXEBBNVGN-UHFFFAOYSA-N |
| Solubility | 10 mm in DMSO |
| Appearance | Solid |
| LogP | -0.60 |
- Product Specification
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
Computed Properties | |
|---|---|
| XLogP3 | -0.8 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 15 |
| Exact Mass | 369.16483347 g/mol |
| Monoisotopic Mass | 369.16483347 g/mol |
| Topological Polar Surface Area | 109Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 529 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CZ-2020132-A3 | Glycopolymer, method of its preparation and its use as a medicine | 2020-03-12 |
| CZ-2020137-A3 | Glycopolymer, method of its preparation and its use as a medicine | 2020-03-12 |
| CN-114761799-A | Methods for Characterizing Target Polypeptides Using Nanopores | 2019-12-02 |
| US-2023024319-A1 | Method of characterising a target polypeptide using a nanopore | 2019-12-02 |
| CZ-2019572-A3 | Glycopolymer, method of its preparation and its use as a medicine | 2019-09-09 |
Applications of Fluorescent Probes & Dyes
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