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Azido-PEG11-amine | 1800414-71-4
| Catelog Number | R14-0260 |
| Category | Azides |
| Molecular Formula | C24H50N4O11 |
| Molecular Weight | 570.67 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0260 | -- | $-- |
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Product Introduction
Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Information |
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|---|---|
| Synonyms | 35-azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-amine; 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido-; Azido-PEG11-NH2; N3-PEG11-CH2CH2NH2 |
| Purity | >97% |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=N)N |
| InChI | InChI=1S/C24H51N4O11/c25-1-3-29-5-7-31-9-11-33-13-15-35-17-19-37-21-23-39-24-22-38-20-18-36-16-14-34-12-10-32-8-6-30-4-2-27-28-26/h26H,1-25H2/q+1 |
| InChI Key | XSNNFLVNOIPCFW-UHFFFAOYSA-N |
| Appearance | Colorless or Light Yellowish Liquid |
| LogP | 0.59106 |
Product Specification |
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|---|---|
| Storage | Store at 2-8°C |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
| Precautionary Statement Codes | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| XLogP3 | -1.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 35 |
| Exact Mass | 570.34760842 g/mol |
| Monoisotopic Mass | 570.34760842 g/mol |
| Topological Polar Surface Area | 142Ų |
| Heavy Atom Count | 39 |
| Formal Charge | 0 |
| Complexity | 507 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022272307-A1 | Bifunctional folate receptor binding compounds | 2021-06-24 |
| US-2021322331-A1 | Nanocapsules for the delivery of cell modulating agents | 2018-12-23 |
| CN-113544270-A | Nanocapsules for delivery of cell modulators | 2018-12-23 |
| JP-2022514956-A | Nanocapsules for delivery of cell regulators | 2018-12-23 |
| ES-2747842-T3 | Ligand-modified double-stranded nucleic acids | 2014-12-15 |
Applications of Fluorescent Probes & Dyes
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