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Azido-PEG10-amine | 912849-73-1
| Catelog Number | R14-0261 |
| Category | Azides |
| Molecular Formula | C22H46N4O10 |
| Molecular Weight | 526.62 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0261 | -- | $-- |
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Product Introduction
Azido-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Information |
|
|---|---|
| Synonyms | N3-PEG10-CH2CH2NH2; 32-Azido-3,6,9,12,15,18,21,24,27,30-decaoxadotriacontan-1-amine; O-(2-Aminoethyl)-O-(2-azidoethyl)nonaethylene Glycol; N3-PEG10-NH2 |
| Purity | >97% |
| IUPAC Name | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
| Canonical SMILES | C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])N |
| InChI | InChI=1S/C22H46N4O10/c23-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-25-26-24/h1-23H2 |
| InChI Key | RMNAJNJBCBFOKX-UHFFFAOYSA-N |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| Appearance | Light yellow liquid |
| LogP | 0.57446 |
Product Specification |
|
|---|---|
| Storage | Store at 2-8°C |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Computed Properties | |
|---|---|
| XLogP3 | -1.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 13 |
| Rotatable Bond Count | 32 |
| Exact Mass | 526.32139368 g/mol |
| Monoisotopic Mass | 526.32139368 g/mol |
| Topological Polar Surface Area | 133Ų |
| Heavy Atom Count | 36 |
| Formal Charge | 0 |
| Complexity | 463 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2022219409-A2 | Compositions containing nucleic acid nanoparticles and processes related to alteration of their physicochemical characteristics | 2021-04-15 |
| US-2021330810-A1 | Compositions containing nucleic acid nanoparticles with modular functionality | 2020-04-27 |
| US-11357865-B2 | Compositions containing nucleic acid nanoparticles with modular functionality | 2020-04-27 |
| US-2022370635-A1 | Compositions containing nucleic acid nanoparticles with modular functionality | 2020-04-27 |
| CN-115315436-A | Modified IL-2 polypeptides and uses thereof | 2020-01-10 |
Applications of Fluorescent Probes & Dyes
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