Azido-PEG1-acid | 1393330-34-1
Catalog Number | R14-0290 |
Category | Azides |
Molecular Formula | C5H9N3O3 |
Molecular Weight | 159.14 |
Catalog Number | Size | Price | Quantity |
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R14-0290 | -- | $-- |
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Product Introduction
Azido-PEG1-C2-acid is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG1-C2-acid can be used in the synthesis of a series of PROTACs.
Chemical Information |
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Related CAS | 1167575-20-3 (polymer) |
Synonyms | N3-PEG1-COOH; Azido-PEG1-C2-acid; Propanoic acid, 3-(2-azidoethoxy)- |
Purity | >95% |
IUPAC Name | 3-(2-azidoethoxy)propanoic acid |
Canonical SMILES | C(COCCN=[N+]=[N-])C(=O)O |
InChI | InChI=1S/C5H9N3O3/c6-8-7-2-4-11-3-1-5(9)10/h1-4H2,(H,9,10) |
InChI Key | JKOVLUVEHHGAEW-UHFFFAOYSA-N |
Solubility | Water, DMSO, DMF, DCM |
Appearance | Transparent Liquid |
- Product Specification
Storage | Store at 2-8°C |
Computed Properties | |
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XLogP3 | 0.5 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 6 |
Exact Mass | 159.06439116 g/mol |
Monoisotopic Mass | 159.06439116 g/mol |
Topological Polar Surface Area | 60.9Ų |
Heavy Atom Count | 11 |
Formal Charge | 0 |
Complexity | 164 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Patents
Publication Number | Title | Priority Date |
---|---|---|
US-2012225089-A1 | Novel conjugates, preparation thereof, and therapeutic use thereof | 2009-06-29 |
US-8952147-B2 | Conjugates, preparation thereof, and therapeutic use thereof | 2009-06-29 |
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