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Aminooxy-PEG3-azide | 1306615-51-9
| Catalog Number | R14-0255 |
| Category | Azides |
| Molecular Formula | C8H18N4O4 |
| Molecular Weight | 234.25 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0255 | -- | $-- |
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Product Introduction
Aminooxy-PEG3-azide is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-C2-PEG3-azide is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Chemical Information |
|
|---|---|
| Synonyms | O-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)hydroxylamine |
| Purity | ≥98% |
| Shelf Life | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| IUPAC Name | O-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]hydroxylamine |
| Canonical SMILES | C(COCCOCCOCCON)N=[N+]=[N-] |
| InChI | InChI=1S/C8H18N4O4/c9-12-11-1-2-13-3-4-14-5-6-15-7-8-16-10/h1-8,10H2 |
| InChI Key | WSRXFPCTWIFEOF-UHFFFAOYSA-N |
| Solubility | 10 mm in DMSO |
| LogP | 0.38986 |
- Product Specification
| Storage | Store at -5°C,keep in dry and avoid sunlight. |
Computed Properties | |
|---|---|
| XLogP3 | -0.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 12 |
| Exact Mass | 234.13280507 g/mol |
| Monoisotopic Mass | 234.13280507 g/mol |
| Topological Polar Surface Area | 77.3Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 187 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-2019100518-A1 | Indole structure-selective crosslinking agent and composite in which same is used | 2016-03-09 |
| WO-2017049275-A2 | Polynucleotides containing a stabilizing tail region | 2015-09-17 |
| WO-2017049286-A1 | Polynucleotides containing a morpholino linker | 2015-09-17 |
| RU-2703456-C2 | Phenyltetrahydroisoquinoline compound, substituted with heteroaryl | 2014-07-25 |
| AU-2014356126-A1 | Methods for oxime conjugation to ketone-modified polypeptides | 2013-11-26 |
Applications of Fluorescent Probes & Dyes
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