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Aminooxy-PEG2-azide | 1043426-13-6
| Catalog Number | R14-0256 |
| Category | Azides |
| Molecular Formula | C6H14N4O3 |
| Molecular Weight | 190.20 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R14-0256 | -- | $-- |
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Product Introduction
Aminooxy-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Chemical Information |
|
|---|---|
| Synonyms | O-(2-(2-(2-azidoethoxy)ethoxy)ethyl)hydroxylamine |
| Purity | >98% |
| Shelf Life | -20°C 3 years powder; -80°C 2 years in solvent |
| IUPAC Name | O-[2-[2-(2-azidoethoxy)ethoxy]ethyl]hydroxylamine |
| Canonical SMILES | C(COCCOCCON)N=[N+]=[N-] |
| InChI | InChI=1S/C6H14N4O3/c7-10-9-1-2-11-3-4-12-5-6-13-8/h1-6,8H2 |
| InChI Key | GCURLNTZWQFVMK-UHFFFAOYSA-N |
| Solubility | 10 mm in DMSO |
- Product Specification
| Storage | -20°C |
Computed Properties | |
|---|---|
| XLogP3 | -0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 9 |
| Exact Mass | 190.10659032 g/mol |
| Monoisotopic Mass | 190.10659032 g/mol |
| Topological Polar Surface Area | 68.1Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 149 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-10029014-B2 | Synthesis of novel asymmetric bow-tie PAMAM dendrimer-based conjugates for tumor-targeting drug delivery | 2013-09-10 |
| US-2016220688-A1 | Synthesis of novel asymmetric bow-tie pamam dendrimer-based conjugates for tumor-targeting drug delivery | 2013-09-10 |
Applications of Fluorescent Probes & Dyes
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