7-Methoxycoumarin-4-acetic acid | 62935-72-2

Name: 7-Methoxycoumarin-4-acetic acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog Number	Size	Price	Quantity
F06-0004	--	$--

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Product Introduction

Key intermidiate for the synthesis of fluorescence probes in chromatographic detection. Shows local anesthetic activity.

Synonyms	7-Methoxy-2-oxo-2H-1-benzopyran-4-acetic acid; Mca-OH; 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid; 2-(7-methoxy-2-oxo-2H-chromen-4-yl)acetic acid; 2H-1-Benzopyran-4-acetic acid, 7-methoxy-2-oxo-; Mca-OH
Purity	≥ 98% (HPLC)
IUPAC Name	2-(7-methoxy-2-oxochromen-4-yl)acetic acid
Canonical SMILES	COC1=CC2=C(C=C1)C(=CC(=O)O2)CC(=O)O
InChI	InChI=1S/C12H10O5/c1-16-8-2-3-9-7(4-11(13)14)5-12(15)17-10(9)6-8/h2-3,5-6H,4H2,1H3,(H,13,14)
InChI Key	ZEKAXIFHLIITGV-UHFFFAOYSA-N
Solubility	Slightly soluble in Acetone, DMSO, Methanol
Density	1.367±0.06 g/cm3 (Predicted)
Appearance	Off-white to light yellow powder
Boiling Point	472.9±45.0 °C (Predicted)
Melting Point	185-195 °C

Excitation	323
Emission	382
Storage	Store at 2-8 °C
Signal	Warning
GHS Hazard Statements	H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement Codes	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.)

Computed Properties
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	3
Exact Mass	234.05282342 g/mol
Monoisotopic Mass	234.05282342 g/mol
Topological Polar Surface Area	72.8Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	360
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PMID	Publication Date	Title	Journal
21695046	2011-01-01	Substrate specifity profiling of the Aspergillus fumigatus proteolytic secretome reveals consensus motifs with predominance of Ile/Leu and Phe/Tyr	PloS one
21931748	2011-01-01	Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatis	PloS one
19674479	2009-08-13	Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival	Molecular brain
18260641	2008-03-04	Small changes in the primary structure of transportan 10 alter the thermodynamics and kinetics of its interaction with phospholipid vesicles	Biochemistry
15642138	2005-01-01	Local expression of matrix metalloproteinases, cathepsins, and their inhibitors during the development of murine antigen-induced arthritis	Arthritis research & therapy

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CN-113999290-A	A kind of high stability leuprolide acetate and application thereof	2021-12-29
CN-113999290-B	A kind of stable leuprolide acetate and application thereof	2021-12-29
CN-113699212-A	Method and screening model for screening new coronavirus main protease small-molecule inhibitor	2021-07-01
US-2022315614-A1	Reducing agents and uses thereof	2021-03-19
US-2022308043-A1	Fluorescent probes for identification and quantification of hepatic transporters in vitro and in vivo	2021-03-16