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Nile Red | 7385-67-3
| Catelog Number | A16-0144 |
| Category | Lipid Fluorescent Probes |
| Molecular Formula | C20H18N2O2 |
| Molecular Weight | 318.37 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0144 | -- | $-- |
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Product Introduction
Nile Red is an aphotostable and lipophilic stain for intracellular lipids and hydrophobic domains of proteins and also for staining of lysosomal phospholipid inclusions.
Chemical Information |
|
|---|---|
| Synonyms | Nile Blue A Oxazone |
| IUPAC Name | 9-(diethylamino)benzo[a]phenoxazin-5-one |
| Canonical SMILES | CCN(CC)C1=CC2=C(C=C1)N=C3C4=CC=CC=C4C(=O)C=C3O2 |
| InChI | InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3 |
| InChI Key | VOFUROIFQGPCGE-UHFFFAOYSA-N |
| Appearance | Solid Powder |
Product Specification |
|
|---|---|
| Excitation | 552 |
| Application | Used as a polarity-sensitive fluorescent probe of lipids and proteins. |
Computed Properties | |
|---|---|
| XLogP3 | 3.8 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 318.136827821 g/mol |
| Monoisotopic Mass | 318.136827821 g/mol |
| Topological Polar Surface Area | 41.9Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 564 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22846507 | 2012-12-01 | Detection of apoptosis through the lipid order of the outer plasma membrane leaflet | Biochimica et biophysica acta |
| 23084897 | 2012-12-01 | Aggregate formation and radiolytic degradation of amphiphilic DNA block copolymer possessing disulfide bond | Bioorganic & medicinal chemistry letters |
| 22407940 | 2012-11-01 | Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS | NMR in biomedicine |
| 22985718 | 2012-11-01 | An improved high-throughput Nile red fluorescence assay for estimating intracellular lipids in a variety of yeast species | Journal of microbiological methods |
| 22989909 | 2012-10-15 | Novel fluorescent ceramide derivatives for probing ceramidase substrate specificity | Bioorganic & medicinal chemistry |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115226785-A | A kind of O/W fat gel and its preparation method and 3D printing application | 2022-07-29 |
| CN-115029307-A | A method to delay the aging of MSCs | 2022-07-28 |
| CN-115212123-A | A kind of plant extract composition for inhibiting sebum secretion and its preparation method and application | 2022-07-28 |
| CN-115141220-A | An Aza-BODIPY compound and its application in nanoparticle tracking in vivo | 2022-07-22 |
| CN-115226898-A | A kind of bile system of small intestine slow-release erythromycin and its preparation method and application | 2022-07-22 |
Applications of Fluorescent Probes & Dyes
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