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N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide | CAS 109628-27-5
| Catalog Number | A14-0058 |
| Category | Calcium, Chloride and Other indicators |
| Molecular Formula | C17H16N2O3S |
| Molecular Weight | 328.39 |
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Product Introduction
N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is a fluorescent probe that features a quinoline-based chromophore, known for its ability to participate in energy transfer processes. This compound contains a methoxy group that contributes to its distinct spectral behavior, allowing it to exhibit specific excitation and emission properties suitable for fluorescence microscopy and imaging workflows. As a labeling reagent, it is used in biochemical assays and molecular tracking, where its conjugation characteristics enable effective interaction with biomolecules.
Chemical Information
Product Specification
Application
Chemical Information
| Synonyms | TSQ; N-(6-methoxyquinolin-8-yl)-4-methylbenzenesulfonamide |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC2=C3C(=CC(=C2)OC)C=CC=N3 |
| InChI | InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3 |
| InChIKey | HKRNYOZJJMFDBV-UHFFFAOYSA-N |
Product Specification
| Excitation | 565 |
| Emission | 590 |
Application
N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is a compound of interest in bioscience research due to its versatile applications. Here are some key applications of N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide:
Fluorescent Probes: N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide can be used as a fluorescent probe in cellular imaging. Its unique fluorescent properties enable the visualization of biological molecules and cellular structures under a microscope. This application is critical for studying the spatial and temporal dynamics of cellular processes.
Enzyme Inhibition Studies: The compound is employed to study enzyme inhibition, particularly in enzymatic assays and mechanistic studies. By inhibiting specific enzymes, researchers can dissect biochemical pathways and understand enzyme functions. This knowledge is invaluable for drug discovery and therapeutic development.
Metal Ion Detection: N-(6-Methoxy-8-Quinolyl)-p-Toluenesulfonamide is used in the detection and quantification of metal ions in biological and environmental samples. Its chelation properties allow it to bind selectively to metal ions, causing a measurable change in fluorescence. This application is essential for monitoring metal ion concentrations and understanding their roles in various biological processes.
Pharmacological Research: The compound serves as a chemical tool in pharmacological studies to explore the effects of potential drug candidates. By targeting specific proteins or pathways, researchers can investigate the pharmacodynamics and pharmacokinetics of new compounds. This aids in the optimization and development of effective therapeutic agents.
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