H-Gly-Gly-AMC

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H-Gly-Gly-AMC

H-Gly-Gly-AMC | CAS 208645-74-3

Catalog Number A18-0051
Category Fluorescent Enzyme Substrates
Molecular Formula C14H15N3O4
Molecular Weight 289.3
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Product Introduction

Gly-Gly-AMC is a fluorogenic substrate for detecting the activity of bacterial proteases from P. aeruginosa and S. aureus. AMC (7-amino-4-methylcoumarin) is released and its fluorescence can be used to quantify the protease activity.

  • Chemical Information

  • Product Specification

  • Application

  • Computed Properties

  • Patents

Synonyms Glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-glycinamide
Purity ≥98%
IUPAC Name 2-amino-N-[2-[(4-methyl-2-oxochromen-7-yl)amino]-2-oxoethyl]acetamide
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CNC(=O)CN
InChI InChI=1S/C14H15N3O4/c1-8-4-14(20)21-11-5-9(2-3-10(8)11)17-13(19)7-16-12(18)6-15/h2-5H,6-7,15H2,1H3,(H,16,18)(H,17,19)
InChIKey LPLILQIZVFKNJC-UHFFFAOYSA-N
Appearance Solid Powder
Excitation 340-360 nm
Emission 440-460 nm
Storage Store at -20°C
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 4
Exact Mass 289.10625597 g/mol
Monoisotopic Mass 289.10625597 g/mol
Topological Polar Surface Area 111Ų
Heavy Atom Count 21
Formal Charge 0
Complexity 475
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Publication Number Title Priority Date
WO-2009009773-A1 Use of otubain enzyme to cleave lysine-48-linked polyubiquitin 2007-07-11
US-6017768-A Combinatorial dihydrobenzopyran library 1994-05-06
US-6790965-B1 Combinatorial dihydrobenzopyran library 1994-05-06

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