H-Gly-Gly-AMC | 208645-74-3
Catelog Number | A18-0051 |
Category | Fluorescent Enzyme Substrates |
Molecular Formula | C14H15N3O4 |
Molecular Weight | 289.3 |
Catalog Number | Size | Price | Quantity |
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A18-0051 | -- | $-- |
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Product Introduction
Gly-Gly-AMC is a fluorogenic substrate for detecting the activity of bacterial proteases from P. aeruginosa and S. aureus. AMC (7-amino-4-methylcoumarin) is released and its fluorescence can be used to quantify the protease activity.
Chemical Information |
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Synonyms | Glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-glycinamide |
Purity | ≥98% |
IUPAC Name | 2-amino-N-[2-[(4-methyl-2-oxochromen-7-yl)amino]-2-oxoethyl]acetamide |
Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)CNC(=O)CN |
InChI | InChI=1S/C14H15N3O4/c1-8-4-14(20)21-11-5-9(2-3-10(8)11)17-13(19)7-16-12(18)6-15/h2-5H,6-7,15H2,1H3,(H,16,18)(H,17,19) |
InChI Key | LPLILQIZVFKNJC-UHFFFAOYSA-N |
Appearance | Solid Powder |
Product Specification |
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Excitation | 340-360 nm |
Emission | 440-460 nm |
Storage | Store at -20°C |
Computed Properties | |
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Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 4 |
Exact Mass | 289.10625597 g/mol |
Monoisotopic Mass | 289.10625597 g/mol |
Topological Polar Surface Area | 111Ų |
Heavy Atom Count | 21 |
Formal Charge | 0 |
Complexity | 475 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Patents
Publication Number | Title | Priority Date |
---|---|---|
WO-2009009773-A1 | Use of otubain enzyme to cleave lysine-48-linked polyubiquitin | 2007-07-11 |
US-6017768-A | Combinatorial dihydrobenzopyran library | 1994-05-06 |
US-6790965-B1 | Combinatorial dihydrobenzopyran library | 1994-05-06 |
Applications of Fluorescent Probes & Dyes
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