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DASPEI | 3785-01-1
| Catelog Number | A16-0192 |
| Category | Mitochondrial Fluorescent Probes |
| Molecular Formula | C17H21IN2 |
| Molecular Weight | 380.27 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0192 | -- | $-- |
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Product Introduction
DASPEI is a cationic styryl mitochondrial dye with a large Stokes shift and can be used for staining of presyntptic nerve terminals independent of neuronal activity.
Chemical Information |
|
|---|---|
| Synonyms | 2-(4-(Dimethylamino)styryl)-1-ethylpyridinium iodide |
| Purity | ≥99% (HPLC) |
| IUPAC Name | 4-[(E)-2-(1-ethylpyridin-1-ium-2-yl)ethenyl]-N,N-dimethylaniline;iodide |
| Canonical SMILES | CC[N+]1=CC=CC=C1C=CC2=CC=C(C=C2)N(C)C.[I-] |
| InChI | InChI=1S/C17H21N2.HI/c1-4-19-14-6-5-7-17(19)13-10-15-8-11-16(12-9-15)18(2)3;/h5-14H,4H2,1-3H3;1H/q+1;/p-1 |
| InChI Key | AMAXNNVXIBDEMV-UHFFFAOYSA-M |
| Solubility | DMSO,Methanol |
| Appearance | Solid Powder |
| Melting Point | 267 °C (dec.) (lit.) |
| MDL Number | MFCD00011994 |
| NACRES | NA.47 |
Product Specification |
|
|---|---|
| Excitation | 355 |
| Emission | 430 |
| Properties Quality Level | 100 |
| Storage | -20°C |
| Application | 2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish. |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
| Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
Computed Properties | |
|---|---|
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 380.07495 g/mol |
| Monoisotopic Mass | 380.07495 g/mol |
| Topological Polar Surface Area | 7.1Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 277 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| WO-2021079962-A1 | Pharmaceutical composition for prevention and/or treatment of hearing loss | 2019-10-24 |
| US-2019311703-A1 | Acoustic trauma system for larval fish | 2018-04-04 |
| US-2019209019-A1 | Thermographic device for measurement of differential temperatures in tissue | 2017-12-08 |
| WO-2019113460-A2 | Thermographic device for measurement of differential temperatures in tissue | 2017-12-08 |
| EP-3758592-A2 | Thermographic device for measurement of differential temperatures in tissue | 2017-12-08 |
Applications of Fluorescent Probes & Dyes
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