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Acridine Orange Base | 494-38-2
| Catelog Number | A19-0003 |
| Category | DNA Stains |
| Molecular Formula | C17H19N3 |
| Molecular Weight | 265.35 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A19-0003 | -- | $-- |
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Product Introduction
Acridine orange is a cell-permeable fluorescent probe that stain nucleic acid. Acridine orange is widely used for cell cycle determination and detection of cellular autophagy.
Chemical Information |
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|---|---|
| Related CAS | 65-61-2 (monohydrochloride) |
| Synonyms | 3,6-Acridinediamine, N3,N3,N6,N6-tetramethyl-; N3,N3,N6,N6-tetramethyl-3,6-acridinediamine; Euchrysine; Waxoline Orange A; 3,6-Acridinediamine, N,N,N',N'-tetramethyl-; Acridine, 3,6-bis(dimethylamino)-; 3,6-Bis(dimethylamino)acridine; 3,6-Di(dimethylamino)acridine; Acridine orange free base; Brilliant Acridine Orange E; C.I. 46005B; C.I. Solvent Orange 15; NSC 194350; Solvent Orange 15; Acridine Orange Stain; Acridine Orange |
| Purity | ≥95% |
| IUPAC Name | 3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine |
| Canonical SMILES | CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C |
| InChI | InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3 |
| InChI Key | DPKHZNPWBDQZCN-UHFFFAOYSA-N |
| Solubility | Soluble in DMF, DMSO, Ethanol, PBS (pH 7.2) |
| Density | 1.169±0.06 g/cm3 |
| Appearance | Yellow Crystalline Solid |
| Boiling Point | 468.6±25.0°C at 760 mmHg |
| Melting Point | 181-182°C |
Product Specification |
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|---|---|
| Excitation | 502 nm (dsDNA), 460 nm (ssDNA and RNA), 475 nm (low pH) |
| Emission | 525 nm (dsDNA), 650 nm (ssDNA and RNA), 590 nm (low pH) |
| Storage | Store at -20°C |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 36126548 | 2022-10-15 | Long-term BPA exposure leads to bone malformation and abnormal expression of MAPK/Wnt/FoxO signaling pathway genes in zebrafish offspring | Ecotoxicology and environmental safety |
| 29975445 | 2018-08-01 | Antiapoptotic effects of vitamins C and E against cypermethrin-induced oxidative stress and spermatogonial germ cell apoptosis | Journal of biochemical and molecular toxicology |
| 25151148 | 2014-11-01 | Enhanced cellular uptake of a TAT-conjugated peptide inhibitor targeting the polo-box domain of polo-like kinase 1 | Amino acids |
| 22992911 | 2013-01-01 | Sperm chromatin structure assay (SCSA®) | Methods in molecular biology (Clifton, N.J.) |
| 23038670 | 2012-11-05 | Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups | Chembiochem : a European journal of chemical biology |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-115233445-A | A method for visible light-catalyzed antibacterial and durable finishing of silk | 2022-08-25 |
| CN-115167075-A | Disperse dye macromolecule-initiated photopolymer, grating and preparation method thereof | 2022-08-08 |
| CN-115172600-A | A kind of organic solar cell and preparation method thereof | 2022-07-25 |
| CN-115177604-A | Application of an astragalus isoflavane in the preparation of drugs for protecting the biological stability of BMSCs | 2022-07-13 |
| CN-114958744-A | A kind of in vitro stem cell expansion culture method and application | 2022-07-12 |
Applications of Fluorescent Probes & Dyes
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