Ac-DNLD-AMC | 958001-92-8

Catalog Number	A18-0040
Category	Fluorescent Enzyme Substrates
Molecular Formula	C30H38N6O12
Molecular Weight	674.7

Catalog Number	Size	Price	Quantity
A18-0040	--	$--

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Product Introduction

Ac-DNLD-AMC is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify caspase-3 activity.

Chemical Information
Synonyms	N-Acetyl-Asp-Asn-Leu-Asp-7-amido-Methylcoumarin; N-acetyl-L-α-aspartyl-L-asparaginyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-α-asparagine
Purity	≥95%
IUPAC Name	(3S)-3-acetamido-4-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-3-carboxy-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid
Canonical SMILES	CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(CC(=O)O)NC(=O)C
InChI	InChI=1S/C30H38N6O12/c1-13(2)7-18(34-29(46)19(10-23(31)38)35-30(47)20(11-24(39)40)32-15(4)37)28(45)36-21(12-25(41)42)27(44)33-16-5-6-17-14(3)8-26(43)48-22(17)9-16/h5-6,8-9,13,18-21H,7,10-12H2,1-4H3,(H2,31,38)(H,32,37)(H,33,44)(H,34,46)(H,35,47)(H,36,45)(H,39,40)(H,41,42)/t18-,19-,20-,21-/m0/s1
InChI Key	IBRRXVTUFUKLDZ-TUFLPTIASA-N

Product Specification

Storage

Store at -20°C

Computed Properties
XLogP3	-1.9
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	17
Exact Mass	674.25477067 g/mol
Monoisotopic Mass	674.25477067 g/mol
Topological Polar Surface Area	290Å²
Heavy Atom Count	48
Formal Charge	0
Complexity	1330
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Applications of Fluorescent Probes & Dyes

Laser Dye

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Ac-DNLD-AMC | 958001-92-8

Product Introduction

Chemical Information

Computed Properties