Tetramethylrhodamine ethyl ester perchlorate

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Tetramethylrhodamine ethyl ester perchlorate

Tetramethylrhodamine ethyl ester perchlorate

Tetramethylrhodamine ethyl ester perchlorate
Catalog Number Size Price Quantity
A16-0054 -- $--

Tetramethylrhodamine ethyl ester (TMRE) perchlorate is a cell-permeant red fluorescent probe commonly used to monitor membrane potential of mitochondria using live cell fluorescence microscopy and flow cytometry. TMRE is a lipophilic cation accumulated by mitochondria and exhibits a red shift in the emission of 575 nm. However, when the membrane is depolarized, as in apoptosis, TMRE is not accumulated in the mitochondria. Thus, the strength of the fluorescence signal in mitochondria is used to assess cell viability.

Chemical Information
Catelog Number: A16-0054
Product Name: Tetramethylrhodamine ethyl ester perchlorate
CAS Number: 115532-52-0
Molecular Formula: C26H27N2O3·ClO4
Molecular Weight: 515.0
Purity: ≥98%
Synonyms: TMRE Perchlorate; TMR ethyl ester perchlorate; 3,6-bis(dimethylamino)-9-[2-(ethoxycarbonyl)phenyl]-xanthylium perchlorate
Product Specification
Appearance: Solid Powder
Storage Conditions: Store at -20°C
Excitation Maximum (nm): 550
Emission Maximum (nm): 575
Additional Information
InChI: InChI=1S/C26H27N2O3.ClHO4/c1-6-30-26(29)20-10-8-7-9-19(20)25-21-13-11-17(27(2)3)15-23(21)31-24-16-18(28(4)5)12-14-22(24)25;2-1(3,4)5/h7-16H,6H2,1-5H3;(H,2,3,4,5)/q+1;/p-1
InChIKey: NBAOBNBFGNQAEJ-UHFFFAOYSA-M
CanonicalSMILES: CCOC(=O)C1=CC=CC=C1C2=C3C=CC(=[N+](C)C)C=C3OC4=C2C=CC(=C4)N(C)C.[O-]Cl(=O)(=O)=O

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