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Spacer C18 CE Phosphoramidite | 125607-09-2
| Catalog Number | R10-0006 |
| Category | DNA Stains |
| Molecular Formula | C42H61N2O10P |
| Molecular Weight | 784.91 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| R10-0006 | -- | $-- |
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Product Introduction
Hexaethylene glycol phosphoramidite is used to insert a spacer arm in an oligonucleotide and may be added in multiple additions when a longer spacer is required.
Chemical Information |
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|---|---|
| Synonyms | Spacer 18 Amidite; Hexaethylene glycol phosphoramidite; 18-O-(4,4'-Dimethoxytrityl)-hexaethylene glycol-1-[[(2-cyanoethyl)-(N,N-diisopropyl)]-Phosphoramidite; 1,1-bis(4-methoxyphenyl)-1-phenyl-2,5,8,11,14,17-hexaoxanonadecan-19-yl (2-cyanoethyl) diisopropylphosphoramidite; Spacer 18 Phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 19,19-bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl ester; 19,19-Bis(4-methoxyphenyl)-19-phenyl-3,6,9,12,15,18-hexaoxanonadec-1-yl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite; Spacer Phosphoramidite 18; DMT Hexaethylene Glycol phosphoramidite |
| Purity | ≥95.0% |
| IUPAC Name | 3-[2-[2-[2-[2-[2-[2-[bis(4-methoxyphenyl)-phenylmethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
| Canonical SMILES | CC(C)N(C(C)C)P(OCCC#N)OCCOCCOCCOCCOCCOCCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC |
| InChI | InChI=1S/C42H61N2O10P/c1-35(2)44(36(3)4)55(53-22-10-21-43)54-34-32-51-30-28-49-26-24-47-23-25-48-27-29-50-31-33-52-42(37-11-8-7-9-12-37,38-13-17-40(45-5)18-14-38)39-15-19-41(46-6)20-16-39/h7-9,11-20,35-36H,10,22-34H2,1-6H3 |
| InChI Key | ZTCKUVQHKIMCLI-UHFFFAOYSA-N |
| Solubility | good in most organic solvents |
| Appearance | colorless/yellowish oil |
| Boiling Point | 763.6±60.0°C (Predicted) |
- Product Specification
| Storage | Store at -20°C |
Computed Properties | |
|---|---|
| XLogP3 | 5.3 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 12 |
| Rotatable Bond Count | 31 |
| Exact Mass | 784.40638314 g/mol |
| Monoisotopic Mass | 784.40638314 g/mol |
| Topological Polar Surface Area | 119Ų |
| Heavy Atom Count | 55 |
| Formal Charge | 0 |
| Complexity | 949 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| US-10308943-B2 | Compositions with improved intravitreal half-life and uses thereof | 2016-02-08 |
| US-2018127754-A1 | Bivalent antisense oligonucleotides | 2010-03-24 |
| US-5674856-A | Modified oligodeoxyribonucleoditides | 1993-01-29 |
Applications of Fluorescent Probes & Dyes
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