Azido-PEG2-PFP ester | 1393330-37-4

Product Introduction

Azido-PEG2-PFP ester is a mixture of azide-functionalized polyethylene glycol (PEG) derivatives interleaved with pentafluorophenyl (PFP) ester moieties. This special compound is widely used as a coupling agent in the field of bioconjugation chemistry and shows unparalleled potential in efficient biomolecule modification. Whether proteins or peptides, azido-PEG2-PFP esters open up many possibilities for revolutionary applications, including drug delivery systems, targeted therapies, and transformative diagnostics.

Chemical Information
Synonyms	perfluorophenyl 3-(2-(2-azidoethoxy)ethoxy)propanoate;
Purity	≥98%
IUPAC Name	(2,3,4,5,6-pentafluorophenyl) 3-[2-(2-azidoethoxy)ethoxy]propanoate
Canonical SMILES	C(COCCOCCN=[N+]=[N-])C(=O)OC1=C(C(=C(C(=C1F)F)F)F)F
InChI	InChI=1S/C13H12F5N3O4/c14-8-9(15)11(17)13(12(18)10(8)16)25-7(22)1-3-23-5-6-24-4-2-20-21-19/h1-6H2
InChI Key	FEXHEMGARNABFF-UHFFFAOYSA-N
Solubility	DMF, DCM
Appearance	Soild powder

Computed Properties
XLogP3	2.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	11
Rotatable Bond Count	11
Exact Mass	369.07479668 g/mol
Monoisotopic Mass	369.07479668 g/mol
Topological Polar Surface Area	59.1Ų
Heavy Atom Count	25
Formal Charge	0
Complexity	453
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Patents

Publication Number	Title	Priority Date
JP-2020114234-A	XTEN conjugated composition and method of making same	2012-02-27