Ac-ANW-AMC

Ac-ANW-AMC, a synthetic substrate employed in enzymatic assays to explore protease activity, finds diverse applications in research and clinical diagnostics.

Protease Activity Assays: Widely utilized in fluorometric assays, Ac-ANW-AMC serves as a pivotal tool for detecting and quantifying protease activity. Upon cleavage by a protease, it liberates a fluorescent product, facilitating the precise measurement of enzyme kinetics and activity levels. This capability is critical for the screening of protease inhibitors and investigating the intricate roles of proteases in a myriad of physiological and pathological processes.

Biotechnology Research: In the realm of biotechnology, Ac-ANW-AMC is instrumental for scrutinizing enzyme specificity and substrate preferences in vitro. By delivering a consistent and quantifiable response, it aids researchers in fine-tuning conditions for protease reactions and evaluating enzyme modifications or mutations. This contributes to the advancement of engineered enzymes with heightened or modified activity, tailored for industrial applications.

Drug Discovery: Acting as a cornerstone in drug development targeting proteases implicated in various diseases, Ac-ANW-AMC plays a crucial role. Through its application in high-throughput screening, researchers can pinpoint potential protease inhibitors that hold promise as therapeutics for ailments ranging from cancer to infectious diseases and inflammatory disorders. It facilitates a deeper comprehension of the efficacy and selectivity of candidate compounds, propelling advancements in pharmaceutical research.

Clinical Diagnostics: In clinical scenarios, Ac-ANW-AMC-based assays are indispensable for evaluating proteolytic activity in biological samples, aiding in diagnosing diseases characterized by altered protease expression or activity.