Ac-ANW-AMC
Catalog Number | A18-0049 |
Category | Fluorescent Enzyme Substrates |
Molecular Formula | C30H32N6O7 |
Molecular Weight | 588.61 |
Catalog Number | Size | Price | Quantity |
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A18-0049 | -- | $-- |
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Product Introduction
Ac-ANW-AMC is a 7-amino-4-methylcoumarin labelled fluorogenic peptidyl substrate and used for measuring chymotrypsin-like activity of the immunoproteasome.
Chemical Information |
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Synonyms | (S)-N1-((S)-3-(1H-indol-3-yl)-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopropan-2-yl)-2-((S)-2-acetamidopropanamido)succinamide; N-Acetyl-L-alanyl-L-asparaginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tryptophanamide; Acetyl-Ala-Asn-Trp-7-amido-4-methylcoumarin |
Purity | >99% |
IUPAC Name | (2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]butanediamide |
Canonical SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C |
InChI | InChI=1S/C30H32N6O7/c1-15-10-27(39)43-25-12-19(8-9-20(15)25)34-29(41)23(11-18-14-32-22-7-5-4-6-21(18)22)36-30(42)24(13-26(31)38)35-28(40)16(2)33-17(3)37/h4-10,12,14,16,23-24,32H,11,13H2,1-3H3,(H2,31,38)(H,33,37)(H,34,41)(H,35,40)(H,36,42)/t16-,23-,24-/m0/s1 |
InChI Key | ORTKHFLJSJQDKO-ZCWWJEROSA-N |
Solubility | Soluble in DMSO |
Density | 1.4±0.1 g/cm3 |
Appearance | Lyophilized Powder |
Boiling Point | 1119.0±65.0°C at 760 mmHg |
- Product Specification
Excitation | 340-360 nm |
Emission | 440-460 nm |
Storage | Store at -20°C |
Computed Properties | |
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XLogP3 | 0.4 |
Hydrogen Bond Donor Count | 6 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 11 |
Exact Mass | 588.23324738 g/mol |
Monoisotopic Mass | 588.23324738 g/mol |
Topological Polar Surface Area | 202Ų |
Heavy Atom Count | 43 |
Formal Charge | 0 |
Complexity | 1140 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 3 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
Applications of Fluorescent Probes & Dyes
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