Ac-ANW-AMC

What We Offer

Ac-ANW-AMC

Ac-ANW-AMC

Catalog Number A18-0049
Category Fluorescent Enzyme Substrates
Molecular Formula C30H32N6O7
Molecular Weight 588.61
Catalog Number Size Price Quantity
A18-0049 -- $--

Product Introduction

Ac-ANW-AMC is a 7-amino-4-methylcoumarin labelled fluorogenic peptidyl substrate and used for measuring chymotrypsin-like activity of the immunoproteasome.

Chemical Information

Synonyms (S)-N1-((S)-3-(1H-indol-3-yl)-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopropan-2-yl)-2-((S)-2-acetamidopropanamido)succinamide; N-Acetyl-L-alanyl-L-asparaginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-tryptophanamide; Acetyl-Ala-Asn-Trp-7-amido-4-methylcoumarin
Purity >99%
IUPAC Name (2S)-2-[[(2S)-2-acetamidopropanoyl]amino]-N-[(2S)-3-(1H-indol-3-yl)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopropan-2-yl]butanediamide
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC(=O)N)NC(=O)C(C)NC(=O)C
InChI InChI=1S/C30H32N6O7/c1-15-10-27(39)43-25-12-19(8-9-20(15)25)34-29(41)23(11-18-14-32-22-7-5-4-6-21(18)22)36-30(42)24(13-26(31)38)35-28(40)16(2)33-17(3)37/h4-10,12,14,16,23-24,32H,11,13H2,1-3H3,(H2,31,38)(H,33,37)(H,34,41)(H,35,40)(H,36,42)/t16-,23-,24-/m0/s1
InChI Key ORTKHFLJSJQDKO-ZCWWJEROSA-N
Solubility Soluble in DMSO
Density 1.4±0.1 g/cm3
Appearance Lyophilized Powder
Boiling Point 1119.0±65.0°C at 760 mmHg
  • Product Specification
Excitation 340-360 nm
Emission 440-460 nm
Storage Store at -20°C

Computed Properties

XLogP3 0.4
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 11
Exact Mass 588.23324738 g/mol
Monoisotopic Mass 588.23324738 g/mol
Topological Polar Surface Area 202Ų
Heavy Atom Count 43
Formal Charge 0
Complexity 1140
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
cartIcon
Inquiry Basket