Phalloidin-TRITC | CAS 915013-10-4

Catalog Number	A16-0002
Category	Cytoskeleton Fluorescent Probes
Molecular Formula	C60H70N12O13S2
Molecular Weight	1231.4

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Product Introduction

Phalloidin-TRITC is a fluorescent cytoskeletal probe for labeling F-actin.

Chemical Information
Product Specification
Application

Synonyms	7-[(4R)-5-[[[[4-[3,6-Bis(dimethylamino)xanthylium-9-yl]-3-carboxyphenyl]amino]thioxomethyl]amino]-4-hydroxy-L-leucine]phalloidin
Purity	≥90%

Excitation	540 nm
Emission	565 nm
Storage	Store at -20°C

Phalloidin-TRITC, a fluorescently labeled toxin extensively utilized in cell biology research to stain and visualize actin filaments, boasts a myriad of applications with intricacy and variability:

Actin Filament Staining: With its specific binding to F-actin, Phalloidin-TRITC allows for the visualization of actin filaments in fixed cells, enabling researchers to explore the intricate cytoskeletal structures and dynamics across diverse cell types. Through fluorescent imaging of actin filaments, researchers gain vital insights into cell shape, motility, and intracellular transport mechanisms, unraveling the complexities of cellular functionality.

Cell Morphology Studies: Utilizing Phalloidin-TRITC to stain the actin cytoskeleton empowers scientists to observe and quantify changes in cell morphology, particularly pivotal in studies delving into cell differentiation, migration, and responses to external stimuli. The precise specificity and fluorescent tagging of Phalloidin-TRITC serve as a potent tool for conducting detailed assessments of cellular morphology, shedding light on cellular behavior and function.

Drug Screening: In the realm of pharmacological research, Phalloidin-TRITC emerges as a critical asset for evaluating the impact of drugs on the actin cytoskeleton. By contrasting stained actin filaments in treated versus untreated cells, researchers can discern compounds that either disrupt or stabilize the cytoskeletal framework. This screening application proves indispensable in drug discovery endeavors, especially in developing treatments aimed at impeding cancer cell motility and invasion, showcasing the substance’s versatile utility in pharmaceutical investigations.

Super-Resolution Microscopy: The integration of Phalloidin-TRITC into cutting-edge imaging techniques like super-resolution microscopy facilitates the attainment of high-resolution visualizations of the actin network, enabling detailed examinations of actin filament organization and spatial relationships within the cytoskeleton. Such intricate imaging capabilities play a pivotal role in unraveling complex cellular processes at the molecular level, offering profound insights into cellular architecture and function with unprecedented clarity and precision.