Inquiry Basket
Laurdan | 74515-25-6
| Catelog Number | A16-0020 |
| Category | Lipid Fluorescent Probes |
| Molecular Formula | C24H35NO |
| Molecular Weight | 353.55 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| A16-0020 | -- | $-- |
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Laurdan is a fluorescent membrane probe that is sensitive to the phospholipid phase transitions of cell membrane. Quantitation of generalized polarization (GP) of laurdan can be used to identify phospholipid phase.
Chemical Information |
|
|---|---|
| Synonyms | 6-Dodecanoyl-2-dimethylaminonaphthalene; 6-Dodecanoyl-N,N-dimethyl-2-naphthylamine; N,N-Dimethyl-6-dodecanoyl-2-naphthylamine |
| Purity | ≥98% |
| Shelf Life | 1 Year |
| IUPAC Name | 1-[6-(dimethylamino)naphthalen-2-yl]dodecan-1-one |
| Canonical SMILES | CCCCCCCCCCCC(=O)C1=CC2=C(C=C1)C=C(C=C2)N(C)C |
| InChI | InChI=1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3 |
| InChI Key | JHDGGIDITFLRJY-UHFFFAOYSA-N |
| Solubility | Soluble in DMF, Acetonitrile, and Methanol |
| Appearance | Solid Powder |
Product Specification |
|
|---|---|
| Storage | Store at -20°C |
Computed Properties | |
|---|---|
| XLogP3 | 8.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 12 |
| Exact Mass | 353.271864740 g/mol |
| Monoisotopic Mass | 353.271864740 g/mol |
| Topological Polar Surface Area | 20.3Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 392 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Literatures
| PMID | Publication Date | Title | Journal |
|---|---|---|---|
| 22889622 | 2012-11-01 | Effect of the addition of alkanols of different topology to dipalmitoyl-phosphatidylcholine vesicles in the presence of gramicidin | Journal of colloid and interface science |
| 22522030 | 2012-10-01 | Interaction of gentamicin polycation with model and cell membranes | Bioelectrochemistry (Amsterdam, Netherlands) |
| 22884687 | 2012-10-01 | Use of the fluorescent probe LAURDAN to label and measure inner membrane fluidity of endospores of Clostridium spp | Journal of microbiological methods |
| 22555243 | 2012-05-03 | Elucidating membrane structure and protein behavior using giant plasma membrane vesicles | Nature protocols |
| 22406142 | 2012-04-01 | Membrane effects of lysozyme amyloid fibrils | Chemistry and physics of lipids |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114634553-A | Cationic peptide C9 and its application | 2022-04-27 |
| WO-2022230354-A1 | Compound, fluorochrome, kit, and cell detection method | 2021-04-26 |
| WO-2022204288-A1 | Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents | 2021-03-24 |
| WO-2022167820-A1 | Methods for measuring the redox potential of proteins | 2021-02-08 |
| WO-2022125673-A1 | Cell-penetrating peptides and peptide complexes and methods of use | 2020-12-09 |
Applications of Fluorescent Probes & Dyes
Get More Product Details?
