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Gadodiamide | CAS 131410-48-5
| Catalog Number | F02-0056 |
| Category | Other Cyanine |
| Molecular Formula | C16H26GdN5O8 |
| Molecular Weight | 573.66 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
Gadodiamide(Omniscan) is a gadolinium-based MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.
Chemical Information
Product Specification
Application
| Synonyms | Gadodiamide, Gd-Dtpa-Bma;Gadodiamide; DV 7572; DV-7572; DV7572; Omniscan; S 041; S-041; S041; |
| Purity | >98% |
| Canonical SMILES | CNC(=O)CN(CCN(CCN(CC(=O)NC)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3] |
| InChI | InChI=1S/C16H29N5O8.Gd/c1-17-12(22)7-20(10-15(26)27)5-3-19(9-14(24)25)4-6-21(11-16(28)29)8-13(23)18-2;/h3-11H2,1-2H3,(H,17,22)(H,18,23)(H,24,25)(H,26,27)(H,28,29);/q;+3/p-3 |
| InChIKey | HZHFFEYYPYZMNU-UHFFFAOYSA-K |
| Excitation | 549, 548, 547 |
| Emission | 554 |
| Storage | 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. |
Gadodiamide is a paramagnetic contrast agent used in magnetic resonance imaging (MRI) to enhance the quality of the images. Here are some key applications of Gadodiamide:
Central Nervous System Imaging: Gadodiamide is widely used for imaging the brain and spinal cord to detect abnormalities such as tumors, multiple sclerosis, and vascular malformations. It helps to increase the visibility of lesions and improve diagnostic accuracy. This allows healthcare providers to make more informed decisions regarding patient care and treatment planning.
Musculoskeletal Imaging: In orthopedic and sports medicine, Gadodiamide is used to improve the visualization of joint structures, including ligaments, cartilage, and tendons. This enhances the detection of injuries such as tears or inflammation that may not be visible on standard MRI scans. Better imaging can lead to precise diagnosis and targeted therapeutic interventions.
Cardiovascular Imaging: Gadodiamide is also employed in the imaging of the heart and blood vessels to assess conditions such as congenital heart disease, myocardial perfusion, and vascular abnormalities. This contrast agent enhances the clarity of blood vessels and cardiac structures, facilitating accurate assessment of cardiovascular health. It aids in planning surgical procedures and monitoring the efficacy of interventions.
Oncology: In cancer diagnostics, Gadodiamide is used to differentiate between benign and malignant tumors, as it helps to delineate tumor boundaries and assess tumor vascularity. Enhanced imaging with Gadodiamide allows for better staging of cancer, guiding biopsy procedures and treatment plans. This is critical in tracking tumor response to therapies and detecting recurrences at early stages.
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