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Specific Fluorescent Stains
Fluorescent Enzyme Substrates
Dnp-RPLALWRS

What We Offer

Dnp-RPLALWRS

Catalog Number	A18-0024
Category	Fluorescent Enzyme Substrates
Molecular Formula	C52H77N17O14
Molecular Weight	1164.3

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* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

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Product Introduction

Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). The activity of MMP-7 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.

Chemical Information
Product Specification
Application

Synonyms	Matrix Metalloproteinase-7 Fluorogenic Substrate; MMP-7 Fluorogenic Substrate; N2-(2,4-dinitrophenyl)-L-arginyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-tryptophyl-L-arginyl-L-serine
Purity	≥95%

Storage

Store at -20°C

Dnp-RPLALWRS, a synthetic peptide renowned for its exceptional biochemical characteristics, finds extensive utility in diverse bioscientific settings. Here are four key applications of Dnp-RPLALWRS:

Peptide Research: Serving as a quintessential model peptide in laboratory environments, Dnp-RPLALWRS is instrumental in delving into protein folding, interactions, and stability. Researchers leverage its properties to delve into peptide conformations and binding affinities, paving the way for advancements in peptide-based therapeutics and biomaterials.

Enzyme Assays: Within the realm of enzyme assays, this peptide plays a pivotal role in analyzing proteolytic activity, particularly in elucidating enzyme specificity and kinetics. By integrating Dnp-RPLALWRS as a substrate, scientists can gauge the activity of specific proteases like trypsin or chymotrypsin. This data is indispensable for unraveling enzyme function and facilitating drug screening processes.

Drug Development: In the arena of drug development, Dnp-RPLALWRS emerges as a valuable tool for screening potential inhibitors of proteolytic enzymes. Its cleavage products, detectable through spectrometric methods, enable high-throughput analysis of compound libraries. This aids in identifying and optimizing novel therapeutic agents targeting specific proteases, driving innovation in drug discovery.

Bioconjugation Studies: Within bioconjugation studies, Dnp-RPLALWRS plays a pivotal role in facilitating the design and synthesis of intricate biomolecules with tailored properties. It can be manipulated to conjugate with diverse molecules, aiding in the comprehension of protein-polymer interactions and the development of cutting-edge biomaterials. These investigations contribute to the creation of advanced biotechnological tools for medical diagnostics and therapeutics, propelling advancements in the field.