![{[Name]}](https://resource.bocsci.com/structure/86701-10-2.gif?v=2025011501)
Inquiry Basket
C6 NBD Ceramide | CAS 94885-02-6
| Catalog Number | A16-0059 |
| Category | Golgi Fluorescent Probes |
| Molecular Formula | C30H49N5O6 |
| Molecular Weight | 575.74 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
C6 NBD Ceramide is a fluorescent ceramide analog containing a nitrobenzoxadiazole (NBD) fluorophore attached to its short six-carbon acyl chain, enabling sensitive detection of lipid movement and metabolic conversion in live or synthetic systems. The NBD moiety provides bright, environment-dependent fluorescence suitable for tracking ceramide trafficking, diffusion, and enzyme activity. Its amphiphilic structure ensures efficient incorporation into lipid membranes without disrupting bilayer integrity. C6 NBD Ceramide is widely used to visualize sphingolipid dynamics, intracellular transport, and the mechanisms of lipid exchange between organelles in real-time fluorescence microscopy studies.
Chemical Information
Product Specification
Application
| Synonyms | N-C6-NBD-D-erythro-Sphingosine; N-[7-(4-nitrobenzo-2-oxa-1,3-diazole)]-6-aminocaproyl-D-erythro-sphingosine |
| Purity | ≥98% |
| Shelf Life | 1 Year |
| IUPAC Name | N-[(E,2S,3R)-1,3-dihydroxyoctadec-4-en-2-yl]-6-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]hexanamide |
| Canonical SMILES | CCCCCCCCCCCCCC=CC(C(CO)NC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])O |
| InChI | InChI=1S/C30H49N5O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-15-18-27(37)25(23-36)32-28(38)19-16-14-17-22-31-24-20-21-26(35(39)40)30-29(24)33-41-34-30/h15,18,20-21,25,27,31,36-37H,2-14,16-17,19,22-23H2,1H3,(H,32,38)/b18-15+/t25-,27+/m0/s1 |
| InChIKey | HZIRBXILQRLFIK-VPZZKNKNSA-N |
| Density | 1.2±0.1 g/cm3 |
| Appearance | Redish Brown Solid |
| Melting Point | >50°C (dec.) |
| Storage | Store at -20°C |
C6 NBD Ceramide, a synthetic analog of natural ceramides coupled with a fluorescent marker, plays a pivotal role in cell biology and neuroscience research. Here are four key applications of C6 NBD Ceramide:
Lipid Metabolism Studies: Delving into the intricate realm of lipid metabolism, researchers utilize C6 NBD Ceramide to investigate the functions of ceramides and their profound effects on cellular activities. By harnessing its fluorescent properties, scientists can visualize the intricate distribution and trafficking of ceramides within cells, unraveling the mysteries of lipid signaling pathways and their implications in complex diseases like obesity and diabetes.
Apoptosis Research: At the forefront of apoptosis research, C6 NBD Ceramide shines as a valuable tool in unraveling the mechanisms of programmed cell death. Through its incorporation into cell cultures, scientists can closely monitor the accumulation of ceramides and their pivotal roles in apoptotic signaling pathways. This exploration is essential for deciphering how ceramides orchestrate cell death in diverse physiological and pathological scenarios, including the intricate landscape of cancer.
Membrane Dynamics: Illuminating the dynamics of membranes, C6 NBD Ceramide emerges as a beacon for studying the organization of lipid rafts and membrane structures. Its fluorescent nature enables researchers to visualize ceramide-enriched domains within the plasma membrane, shedding light on their involvement in crucial cellular processes such as signal transduction, endocytosis, and membrane fusion. This insight fuels a deeper comprehension of membrane biology and associated disorders, guiding future research and therapeutic advancements.
Experimental Therapeutics: Unveiling new horizons in drug development, C6 NBD Ceramide takes center stage in exploring its potential therapeutic applications. With its ability to induce apoptosis, this ceramide analog emerges as a promising candidate for anti-cancer therapies. Researchers delve into assessing the therapeutic efficacy of ceramide analogs, unraveling their impact on cancer cell viability, and laying the groundwork for innovative treatment strategies that hold the promise of revolutionizing cancer care.
Recommended Services
Recommended Articles
- Hoechst Dyes: Definition, Structure, Mechanism and Applications
- Mastering the Spectrum: A Comprehensive Guide to Cy3 and Cy5 Dyes
- Fluorescent Probes: Definition, Structure, Types and Application
- Fluorescent Dyes: Definition, Mechanism, Types and Application
- Coumarin Dyes: Definition, Structure, Benefits, Synthesis and Uses
- BODIPY Dyes: Definition, Structure, Synthesis and Uses
- Cyanine Dyes: Definition, Structure, Types and Uses
- Fluorescein Dyes: Definition, Structure, Synthesis and Uses
- Rhodamine Dyes: Definition, Structure, Uses, Excitation and Emission
- Unlocking the Power of Fluorescence Imaging: A Comprehensive Guide
- Cell Imaging: Definitions, Systems, Protocols, Dyes, and Applications
- Lipid Staining: Definition, Principles, Methods, Dyes, and Uses
- Flow Cytometry: Definition, Principles, Protocols, Dyes, and Uses
- Nucleic Acid Staining: Definition, Principles, Dyes, Procedures, and Uses
- DNA Staining: Definition, Procedures, Benefits, Dyes and Uses
- Cell Staining: Definition, Principles, Protocols, Dyes, and Uses
- Ion Imaging: Definition, Principles, Benefits, Dyes, and Uses
- Fluorescent Labeling: Definition, Principles, Types and Applications
Recommended Products
Online Inquiry
