Boron, [2-​[[4-​(5,​5-​dimethyl-​1,​3,​2-​dioxaborinan-​2-​yl)​phenyl]​(3,​5-​dimethyl-​2H-​pyrrol-​2-​yildene-​κN)​methyl]​-​3,​5-​dimethyl-​1H-​pyrrolato-​κN]​difluoro-​, (T-​4)- | CAS 401470-69-7

Boron, [2-[[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl](3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-3,5-dimethyl-1H-pyrrolato-κN]difluoro-, (T-4)-, a highly functionalized BODIPY derivative, incorporates a unique combination of boron-dipyrromethene (BODIPY) core structure and several distinct substituents, such as a dimethyl dioxaborine group and pyrrole derivatives. The boron atom at the center of the molecule stabilizes the conjugated system, and the specific modifications improve its fluorescence properties, making it a versatile compound for a wide range of applications in scientific research and technology.

This compound is widely utilized in fluorescence imaging and cellular biology. Its strong fluorescence intensity, photostability, and excellent quantum yield make it ideal for live-cell imaging and real-time molecular tracking. The extended conjugation and electron-rich nature of the molecule provide a narrow and stable emission spectrum, allowing for high-resolution imaging and accurate monitoring of biological processes, such as protein localization, intracellular signaling, and cellular dynamics.

In chemical sensing, Boron, [2-[[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl](3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-3,5-dimethyl-1H-pyrrolato-κN]difluoro- is employed as a fluorescent probe for the detection of various analytes, including metal ions, pH changes, and reactive oxygen species (ROS). The presence of the dioxaborine group allows the compound to specifically interact with metal ions or small molecules, while its fluorescent properties enable the sensitive and selective detection of these analytes in complex biological or environmental samples. This versatility in chemical sensing supports a broad range of applications, from diagnostics to environmental monitoring.

The compound also plays a significant role in photodynamic therapy (PDT), where its ability to generate reactive oxygen species (ROS) upon light excitation makes it an effective photosensitizer. In PDT, the molecule is activated by specific wavelengths of light, leading to the production of singlet oxygen and other reactive species that can target and destroy cancer cells or pathogens. Its excellent absorption and emission properties, combined with its ability to selectively accumulate in tumors or infected tissues, make it a promising candidate for therapeutic applications, especially in the treatment of cancer and bacterial infections.

In material science, Boron, [2-[[4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl](3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-3,5-dimethyl-1H-pyrrolato-κN]difluoro- is used in the development of advanced optoelectronic devices, such as organic light-emitting diodes (OLEDs) and organic solar cells. Its strong absorption and fluorescence properties contribute to efficient energy conversion and light emission, making it a valuable material in the design of high-performance electronic and photonic devices. Furthermore, the compound’s molecular stability and tunable properties allow for optimization in various applications, ranging from displays to energy harvesting systems.