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BODIPY FL Alkyne
| Catalog Number | F01-0208 |
| Category | BODIPY |
| Molecular Formula | C17H18BF2N3O |
| Molecular Weight | 329.15 |
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Product Introduction
BODIPY FL Alkyne is a green-fluorescent dye with an alkyne functional group that is reactive with azides in the copper-catalyzed click reaction. This compound is non-ionic, and relatively insensitive to environment and pH changes.
Chemical Information
Product Specification
Application
| Synonyms | EverFluor FL Alkyne; EverFluor FL Propargyl |
| Appearance | Solid Powder |
| Excitation | 430 |
| Emission | 542 |
BODIPY FL Alkyne is a fluorescent dye designed for use in biological and chemical research. This compound features a BODIPY (boron-dipyrromethene) core, which is known for its strong fluorescence and high stability. The alkyne functional group allows for conjugation with other molecules, making BODIPY FL Alkyne a versatile tool for a variety of labeling and detection applications. Its green fluorescence, which is easily detectable in the visible spectrum, makes it an ideal candidate for imaging and tracking in various biological and chemical systems.
One key application of BODIPY FL Alkyne is in click chemistry. The alkyne group enables it to participate in the copper-catalyzed azide-alkyne cycloaddition (CuAAC), a widely used reaction for selective conjugation with azide-containing molecules. This property makes BODIPY FL Alkyne invaluable in chemical biology, where it is used to tag biomolecules, proteins, or other targets with a fluorescent label. This facilitates the visualization and study of molecular interactions and cellular processes in real-time.
Another important application of BODIPY FL Alkyne is in cellular imaging. The dye’s bright fluorescence allows for the tracking of live cells in culture. By conjugating BODIPY FL Alkyne to specific biomolecules or cellular structures, researchers can monitor cellular dynamics, such as protein localization, trafficking, and interactions. This is particularly useful in studying complex processes like cell signaling, endocytosis, and drug delivery. The non-toxic nature of the dye makes it suitable for long-term imaging in live cells.
BODIPY FL Alkyne is also used in proteomics and drug discovery. By labeling peptides, proteins, or small molecules with this fluorescent tag, researchers can study their binding interactions and the effects of drug candidates on specific molecular targets. This application is essential for screening potential drug candidates, understanding protein function, and investigating the mechanisms of action of various compounds in cellular systems.
In addition, BODIPY FL Alkyne is applied in environmental monitoring and chemical sensing. Its ability to form stable conjugates with environmental analytes makes it useful in detecting and tracking pollutants or other chemical substances in water, air, and soil. The fluorescent signal generated by BODIPY FL Alkyne enables sensitive detection and quantification of target compounds, aiding in environmental assessments and pollution control efforts.
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