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BODIPY
BODIPY 630/650 Cadaverine

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BODIPY 630/650 Cadaverine

Catalog Number	F01-0176
Category	BODIPY
Molecular Formula	C28H30BClF2N4O2S
Molecular Weight	570.89

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Product Introduction

BODIPY 630/650 Cadaverine is an aliphatic-amine analog of the red-fluorescent dye, of which the primary amine can be coupled to aldehydes and ketones to yield a reversible Schiff Base product that can be transformed to a stable amine derivative using a reducing agent like sodium borohydride or sodium cyanoborohydride.

Chemical Information
Product Specification
Application

Synonyms	EverFluor 630/650 Cadaverine
Appearance	Solid Powder

Excitation	494
Emission	522

BODIPY 630/650 Cadaverine is a fluorescent dye designed for use in various biological and biochemical applications. The dye features a BODIPY fluorophore that emits in the far-red to near-infrared region of the spectrum, making it ideal for experiments requiring minimal background fluorescence. The cadaverine group is a biogenic amine that enables the dye to specifically conjugate with amine-containing compounds, such as proteins, peptides, and other biomolecules, facilitating targeted labeling.

One key application of BODIPY 630/650 Cadaverine is in live-cell imaging. Due to its far-red fluorescence, the dye allows researchers to monitor cellular processes in real time with minimal interference from autofluorescence, a common issue in visible-range fluorescence. This makes it especially useful in multi-color imaging where other fluorescent probes are used simultaneously. It is often employed to study protein localization, intracellular trafficking, and receptor dynamics within live cells.

BODIPY 630/650 Cadaverine is also valuable in tracking the distribution and dynamics of biomolecules in tissues. Its high brightness and stability enable clear visualization in tissue samples, even in deep tissues, making it a powerful tool for in vivo imaging. This application is commonly used in cancer research, where tracking the movement of specific proteins or biomarkers within tissues can provide insight into tumor progression, metastasis, and drug response.

Another significant application of BODIPY 630/650 Cadaverine is in molecular probes and biosensor development. The ability of the dye to bind to amine-containing compounds makes it an excellent candidate for creating sensors that detect specific molecules in biological systems. Researchers use BODIPY 630/650 Cadaverine-based sensors to monitor environmental changes in the intracellular milieu or to detect specific biochemical reactions, such as enzyme activity or the presence of certain metabolites.

Furthermore, BODIPY 630/650 Cadaverine is utilized in conjugation studies for antibody or protein-labeling applications. By attaching the dye to antibodies or other biomolecules, researchers can track their binding to specific targets, such as antigens or receptors. This application is frequently used in immunoassays, flow cytometry, and immunohistochemistry, providing crucial data on target identification and protein interactions.