BODIPY 558/568 Phalloidin

BODIPY 558/568 Phalloidin, a fluorescent conjugate of phalloidin renowned for its binding affinity to actin filaments, finds extensive utility in scientific research.

Cellular Imaging: Widely adopted in cellular imaging, BODIPY 558/568 Phalloidin enables the visualization and quantification of F-actin structures within cells. By specifically binding to actin filaments, researchers can scrutinize the intricate cytoskeletal arrangements with unparalleled resolution. This pivotal tool underpins the investigation of fundamental cellular processes comprising morphogenesis, motility, and division.

Cytoskeleton Studies: Delving into the cytoskeleton, BODIPY 558/568 Phalloidin aids in discerning alterations in actin filament dynamics across diverse experimental contexts. It affords researchers the opportunity to witness the dynamic responses of actin to various biochemical and mechanical stimuli. This insight is indispensable for unraveling the cytoskeleton’s role in upholding cell morphology and stability.

High-Throughput Screening: Employed in high-throughput screening assays, BODIPY 558/568 Phalloidin assists in the identification of compounds influencing actin polymerization and depolymerization. Leveraging fluorescence-based detection, researchers can evaluate the effects of different chemical agents on actin structures with enhanced efficiency. This avenue facilitates the discovery of novel pharmaceuticals targeting the dynamic actin cytoskeleton.

Tissue Engineering: Within the realm of tissue engineering, BODIPY 558/568 Phalloidin serves as a pivotal tool for assessing the formation and integration of actin networks within 3D scaffolds. Through staining and visualization of actin structures, researchers can appraise the compatibility of diverse biomaterials in supporting cellular proliferation. This application bolsters the design of advanced constructs for regenerative medicine, fostering the evolution of tissue engineering practices.