BDY 650-X, SE

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BDY 650-X, SE

BDY 650-X, SE | 235439-04-0

Catalog Number R01-0008
Category BODIPY
Molecular Formula C33H32BF2N5O6
Molecular Weight 643.44
Catalog Number Size Price Quantity
R01-0008 -- $--

Product Introduction

BDY 650-X, SE is a reagent that can be used as a fluorescent agent for the labeling of amines. It can also be used to create biosensor arrays on micro- and nano-structured surfaces.

Chemical Information

Synonyms BDP 650/665 X NHS ester;(T-4)-[2-[4-[2-[2-[([2,2'-Bi-1H-pyrrol]-5-yl-κN1)methylene]-2H-pyrrol-5-yl-κN]ethenyl]phenoxy]-N-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]acetamidato]difluoroboron
Purity ≥90%
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 6-[[2-[4-[(E)-2-[2,2-difluoro-12-(1H-pyrrol-2-yl)-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-4-yl]ethenyl]phenoxy]acetyl]amino]hexanoate
Canonical SMILES F[B-]1(F)[N+]2=C(C=CC2=CC3=CC=C(C4=CC=CN4)N13)/C=C/C5=CC=C(OCC(NCCCCCC(ON6C(CCC6=O)=O)=O)=O)C=C5
InChI InChI=1S/C33H32BF2N5O6/c35-34(36)39-24(11-12-25(39)21-26-13-16-29(40(26)34)28-5-4-20-37-28)10-7-23-8-14-27(15-9-23)46-22-30(42)38-19-3-1-2-6-33(45)47-41-31(43)17-18-32(41)44/h4-5,7-16,20-21,37H,1-3,6,17-19,22H2,(H,38,42)/b10-7+
InChI Key CDXXFTJLAKSQSR-JXMROGBWSA-N
Solubility Soluble to 64.34 mg/ml in DMSO.
Appearance Solid
  • Product Specification
  • Application
ε, L⋅mol-1⋅cm-1 94000
Fluorescence Quantum Yield 0.52
Excitation 649
Emission 667

BDY 650-X, SE is a highly specialized reagent widely recognized for its exceptional fluorescence properties, making it an invaluable tool in various scientific and industrial applications. As a fluorescent agent, BDY 650-X, SE is primarily employed for the labeling of amines, a fundamental process in biochemistry and molecular biology. By attaching itself to amine groups, this reagent enables the visualization and tracking of biological molecules, facilitating a deeper understanding of complex biochemical processes. Its unique spectral properties, including high quantum yield and photostability, make it a preferred choice for researchers aiming to study cellular processes, protein interactions, and other molecular phenomena through fluorescence microscopy and other imaging techniques.

One of the critical applications of BDY 650-X, SE is in the development of biosensor arrays, especially on micro- and nano-structured surfaces. By incorporating BDY 650-X, SE into these innovative biosensors, scientists can achieve highly sensitive and selective detection of various biomolecules. These biosensor arrays hold significant promise for medical diagnostics, environmental monitoring, and food safety, where detecting minute concentrations of specific substances is crucial. The reagent’s ability to reliably label and detect target molecules on such small scales enhances the performance and accuracy of biosensors, paving the way for breakthroughs in point-of-care testing and real-time analysis.

In addition to its role in biosensor technology, BDY 650-X, SE is also instrumental in drug discovery and development. Researchers utilize this fluorescent reagent to label pharmaceutical compounds and observe their interactions with biological targets in vitro. This application is critical for understanding the mechanisms of action of new drugs, screening potential therapeutic candidates, and optimizing drug design. By enabling the visualization of drug-target interactions at the molecular level, BDY 650-X, SE contributes to the efficient and informed development of novel therapeutic agents, ultimately accelerating the drug discovery pipeline.

Furthermore, BDY 650-X, SE finds application in the field of advanced materials science. Its fluorescence properties are harnessed to study the dynamics and properties of various materials, contributing to the development of new materials with tailored optical and electronic features. Practically, this can lead to the enhancement of materials used in electronic devices, photonic applications, and nanotechnology. By allowing researchers to probe material characteristics with high precision, BDY 650-X, SE supports innovations that require detailed insight into material behavior and structure, thus facilitating advancements in technology and materials engineering.

Computed Properties

Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 14
Exact Mass 643.2413702 g/mol
Monoisotopic Mass 643.2413702 g/mol
Topological Polar Surface Area 126Ų
Heavy Atom Count 47
Formal Charge 0
Complexity 1340
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
WO-2020072491-A1 Brevican-binding peptides for brain tumor imaging 2018-10-01
US-2016121002-A1 Bioorthogonal Turn-on Probes 2013-05-06
US-2020188535-A1 Bioorthogonal Turn-on Probes 2013-05-06
US-2016022817-A1 Photoswitchable HDAC Inhibitors 2013-03-13
US-2019070295-A1 Photoswitchable HDAC Inhibitors 2013-03-13
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