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3-Bodipy-propanoic acid | 165599-63-3
| Catalog Number | F01-0012 |
| Category | BODIPY |
| Molecular Formula | C14H15BF2N2O2 |
| Molecular Weight | 292.093 |
| Catalog Number | Size | Price | Quantity |
|---|---|---|---|
| F01-0012 | 100 mg | $838 |
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Product Introduction
BODIPY dyes are used to generate fluorescent conjugates of proteins, nucleotides, oligonucleotides and dextrans, as well as to prepare fluorescent enzyme substrates, fatty acids, phospholipids, lipopolysaccharides, receptor ligands and polystyrene microspheres.
Chemical Information |
|
|---|---|
| Synonyms | BDP FL carboxylic acid;4,4-Difluoro-5,7-dimethyl-3-(2-carboxyethyl)-4-bora-3a,4a-diaza-S-indacene; 7-(2-carboxyethyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide; BDP FL acid; BODIPY FL |
| Purity | 95% |
| IUPAC Name | 3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)propanoic acid |
| Canonical SMILES | [B-]1(N2C(=CC(=C2C=C3[N+]1=C(C=C3)CCC(=O)O)C)C)(F)F |
| InChI | InChI=1S/C14H15BF2N2O2/c1-9-7-10(2)18-13(9)8-12-4-3-11(5-6-14(20)21)19(12)15(18,16)17/h3-4,7-8H,5-6H2,1-2H3,(H,20,21) |
| InChI Key | BJDJEJIINKBPHY-UHFFFAOYSA-N |
| Solubility | good in DMF, DMSO, alcohols |
| Appearance | Red Solid |
| Melting Point | >180°C(dec.) |
- Product Specification
- Application
- QC Data
| ε, L⋅mol-1⋅cm-1 | 92000 |
| Fluorescence Quantum Yield | 0.97 |
| Excitation | 503 |
| Emission | 509 |
| Storage | - 20 °C for long-term storage |
| Signal | Warning |
| GHS Hazard Statements | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation] |
| Precautionary Statement Codes | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
3-Bodipy-propanoic acid, a versatile fluorescent dye, finds applications across diverse scientific research and technological pursuits. Here are four key applications of 3-Bodipy-propanoic acid:
Fluorescence Imaging: Embraced in fluorescence microscopy, 3-Bodipy-propanoic acid emerges as an indispensable tool for labeling and observing intricate cellular structures and biomolecules. Its vibrant fluorescence and enduring photostability render it an optimal choice for monitoring dynamic processes within live cells. Researchers exploit this dye to scrutinize cellular dynamics, intracellular trafficking, and protein distribution with exceptional spatial and temporal acuity.
FRET Studies: Within fluorescence resonance energy transfer (FRET) assays, 3-Bodipy-propanoic acid assumes dual roles as a donor or acceptor molecule owing to its favorable spectral characteristics. This compound serves as a cornerstone for investigating protein-protein interactions, conformational alterations, and molecular distance measurements. The insights gleaned from this technique unravel molecular mechanisms and interactions fundamental in deciphering intricate cellular pathways.
Biological Sensors: Unveiling its potential in biosensor development, 3-Bodipy-propanoic acid emerges as a sensitive indicator of environmental shifts, such as pH variations, ion concentrations, and polarity changes. This dye is integrated into the sensor frame and notifies changes in the surrounding environment through changes in fluorescence intensity or wavelength.
Environmental Monitoring: Extending beyond biological realms, 3-Bodipy-propanoic acid steps into the realm of environmental surveillance armed with its luminescent properties. This dye facilitates the identification of contaminants like heavy metals and organic compounds within aquatic ecosystems. By crafting tailored probes with this dye, scientists deliver crucial assessments of environmental pollution levels, paving the way for targeted strategies in pollution mitigation and environmental reclamation.
Computed Properties | |
|---|---|
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 292.1194642 g/mol |
| Monoisotopic Mass | 292.1194642 g/mol |
| Topological Polar Surface Area | 45.2Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 586 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
Patents
| Publication Number | Title | Priority Date |
|---|---|---|
| CN-114920717-A | Pimamarane diterpene compound and its preparation method and application | 2022-07-06 |
| CN-115074359-A | Primer-probe combination product for identifying Yehansu and its application | 2022-06-28 |
| CN-114958835-A | Combination product and kit for detection of Bacterial Blight of Rice | 2022-05-25 |
| CN-115029470-A | Combination product and kit for detection of bacterial blight of rice | 2022-05-25 |
| CN-114752663-A | A kind of fluorescence crosstalk correction method and its application | 2022-05-18 |
Applications of Fluorescent Probes & Dyes
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