2,6-Diiodo-1,3,5,7-tetramethyl-8-(4-pyridyl)-4,4-difluoroboradiazasindacene | 1434003-53-8

2,6-Diiodo-1,3,5,7-tetramethyl-8-(4-pyridyl)-4,4-difluoroboradiazasindacene, a modified BODIPY dye, features iodine atoms at the 2- and 6-positions, a pyridyl group at the 8-position, and methyl substitutions. These structural modifications significantly enhance its optical and chemical properties, including strong fluorescence, high photostability, and a heavy atom effect that facilitates intersystem crossing. This unique combination makes it an ideal candidate for applications in imaging, sensing, and therapeutic fields.

This compound is extensively used in fluorescence imaging and microscopy. The pyridyl substitution enhances its water solubility and targeting capabilities, enabling it to serve as a reliable fluorescent probe for visualizing biological structures and processes, particularly in real-time cellular and subcellular imaging.

2,6-Diiodo-BODIPY derivatives are valuable in photodynamic therapy (PDT). The heavy atom effect of iodine promotes intersystem crossing to the triplet state, enhancing singlet oxygen generation. This property makes the compound a highly effective photosensitizer for targeted cancer therapy and antimicrobial treatments, combining imaging and therapeutic functions.

In chemical sensing, this dye is used for detecting specific analytes, such as metal ions and pH changes. The pyridyl group improves binding specificity, while its fluorescence properties allow for sensitive and selective detection in environmental and biomedical applications.

The compound also plays a significant role in material science. It is utilized in the development of advanced optoelectronic devices, including organic solar cells and light-emitting diodes (OLEDs). Its strong light absorption and tunable emission properties contribute to improved energy transfer and device efficiency, making it an essential material for modern technological applications.