1,7-Dimethyl-3,5-bis[4-(N,N-dimethylamino)phenylethenyl]-8-phenyl-4,4-difluoroboradiazasindacene | 1039552-26-5

1,7-Dimethyl-3,5-bis[4-(N,N-dimethylamino)phenylethenyl]-8-phenyl-4,4-difluoroboradiazasindacene, often referred to as a BODIPY derivative, is a fluorescent dye with a broad range of applications in bioscience.

Fluorescent Labeling: This BODIPY derivative is widely used in fluorescent labeling for biomolecules due to its bright fluorescence and photostability. Researchers apply it in tagging proteins, nucleic acids, and other biological macromolecules to visualize their localization and dynamics in live cells. This application is vital for imaging studies in cell biology, allowing for high-resolution tracking of molecular interactions in real-time.

Photodynamic Therapy: The compound also finds application in photodynamic therapy (PDT), a treatment method for cancer that involves light-sensitive drugs. As a photosensitizer, this BODIPY derivative generates reactive oxygen species upon light activation, leading to the targeted destruction of cancer cells. This approach offers a less invasive alternative to conventional cancer therapies with reduced systemic side effects.

Chemical Sensors: 1,7-Dimethyl-3,5-bis[4-(N,N-dimethylamino)phenylethenyl]-8-phenyl-4,4-difluoroboradiazasindacene serves as a chemical sensor due to its ability to detect changes in its environment. It is utilized in sensing applications for detecting pH shifts, metal ions, or other analytes that alter its fluorescence properties.

Cell Imaging and Tracking: In cell imaging, this fluorescent dye is used for long-term tracking of cells in culture and in vivo studies. Its stability under various conditions allows for extended observation periods without significant photobleaching. This capability is essential for monitoring cell proliferation, migration, and interaction in developmental biology and cancer research.