Gly-Gly-Gly-PEG3-TCO

What We Offer

Gly-Gly-Gly-PEG3-TCO

Gly-Gly-Gly-PEG3-TCO | 2353409-81-9

Catelog Number R15-0004
Category TCO
Molecular Formula C23H41N5O8
Molecular Weight 515.60
Catalog Number Size Price Quantity
R15-0004 -- $--

Product Introduction

Gly-Gly-Gly-PEG3-TCO is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Chemical Information

Synonyms Cyclooct-4-en-1-yl (1-amino-6-(2-amino-2-oxoethyl)-2,5-dioxo-9,12,15-trioxa-3,6-diazaheptadecan-17-yl)carbamate
Purity ≥95%
Shelf Life 0-4℃ for short term (days to weeks), or -20℃ for long term (months).
IUPAC Name [(4Z)-cyclooct-4-en-1-yl] N-[2-[2-[2-[2-[[2-[(2-aminoacetyl)amino]acetyl]-(2-amino-2-oxoethyl)amino]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Canonical SMILES C1CC=CCCC(C1)OC(=O)NCCOCCOCCOCCN(CC(=O)N)C(=O)CNC(=O)CN
InChI InChI=1S/C23H41N5O8/c24-16-21(30)27-17-22(31)28(18-20(25)29)9-11-34-13-15-35-14-12-33-10-8-26-23(32)36-19-6-4-2-1-3-5-7-19/h1-2,19H,3-18,24H2,(H2,25,29)(H,26,32)(H,27,30)/b2-1-
InChI Key HXCYFJZPQLRXDG-UPHRSURJSA-N
Solubility 10 mm in DMSO
Appearance Solid

Product Specification

Storage -20°C

Computed Properties

XLogP3 -1.1
Hydrogen Bond Donor Count 5
Hydrogen Bond Acceptor Count 9
Rotatable Bond Count 19
Exact Mass 515.29551328 g/mol
Monoisotopic Mass 515.29551328 g/mol
Topological Polar Surface Area 179Ų
Heavy Atom Count 36
Formal Charge 0
Complexity 677
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
cartIcon
Inquiry Basket