True BLUE chloride

What We Offer

True BLUE chloride

True BLUE chloride | 71431-30-6

Catalog Number A16-0176
Category Other Cell Fluorescent Probes
Molecular Formula C20H18Cl2N4O2
Molecular Weight 417.29
Catalog Number Size Price Quantity
A16-0176 -- $--

Product Introduction

True BLUE chloride is a water-soluble, UV light-excitable, divalent cationic dye that stains the cytoplasm with blue fluorescence.

Chemical Information

Synonyms True blue; 5-Benzofurancarboximidamide, 2,2'-(1E)-1,2-ethenylbis-, dihydrochloride; (E)-2,2'-Vinylenedi-1-benzo(b)furane-5-carboxamidine dihydrochloride 2,2'-(1E)-1,2-ethenediylbis-5-benzofurancarboximidamide, dihydrochloride; 2,2'-(1,2-ethenediyl)bis-dihydrochloride dihydrochloride; 5-Benzofurancarboximidamide,2,2'-(1E)-1,2-ethenediylbis-,hydrochloride(1:2); 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide;dihydrochloride
IUPAC Name 2-[(E)-2-(5-carbamimidoyl-1-benzofuran-2-yl)ethenyl]-1-benzofuran-5-carboximidamide;dihydrochloride
Canonical SMILES C1=CC2=C(C=C1C(=N)N)C=C(O2)/C=C/C3=CC4=C(O3)C=CC(=C4)C(=N)N.Cl.Cl
InChI WFZFMHDDZRBTFH-CZEFNJPISA-N
InChI Key C1=CC2=C(C=C1C(=N)N)C=C(O2)C=CC3=CC4=C(O3)C=CC(=C4)C(=N)N.Cl.Cl
Appearance Solid Powder
  • Application

True BLUE chloride, a highly sensitive stain utilized in diverse biological and biotechnological contexts to visualize or quantify specific biological entities, showcases significant versatility. Here are four key applications of True BLUE chloride:

Histology: Within the realm of histology, True BLUE chloride serves as a cornerstone in staining techniques, offering unparalleled sensitivity for visualizing distinct cellular structures and tissues when examined under a microscope. Its refined specificity makes it an indispensable tool for conducting intricate tissue analyses. This application finds utility in both clinical diagnostics and research scenarios, facilitating a comprehensive comprehension of tissue architecture and pathology.

Neuroscience: In the expansive field of neuroscience, True BLUE chloride finds its purpose in tracing neuronal pathways and intricate connections within the brain and spinal cord. This stain is instrumental in aiding researchers to chart the complex networks of neurons, unraveling the mysteries of neural circuits. Such a technique plays a pivotal role in studying brain functionality, neurodevelopment, and the mechanisms underlying neurodegenerative disorders.

Immunohistochemistry: True BLUE chloride emerges as a vital component in immunohistochemical procedures, acting as an essential substrate to detect specific antigens within tissue sections. Its functionality as a chromogenic agent in enzyme-linked assays produces a distinct blue signal upon interaction with target antigens, facilitating the visualization of protein expression patterns and their spatial distribution in various tissues and cells.

Microbiology: Within microbiological studies, True BLUE chloride can be effectively harnessed to stain bacterial colonies and biofilms, enhancing the visual contrast of microbial samples. This heightened contrast aids researchers in better observing and quantifying microbial growth, morphology, and interactions, shedding light on crucial aspects of microbial ecology, pathogenesis, and the efficacy of antimicrobial interventions.

Computed Properties

Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 4
Exact Mass 416.0806812 g/mol
Monoisotopic Mass 416.0806812 g/mol
Topological Polar Surface Area 126Ų
Heavy Atom Count 28
Formal Charge 0
Complexity 542
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 3
Compound Is Canonicalized Yes

Patents

Publication NumberTitlePriority Date
CA-2686238-A1 Metabotropic glutamate receptor 7(mglur7)-binding antibody 2007-05-15
CA-2686238-C Metabotropic glutamate receptor 7(mglur7)-binding antibody 2007-05-15
JP-2010527921-A Antibody to G protein coupled receptor (GPCR) 2007-05-15
JP-5425056-B2 Antibody to G protein coupled receptor (GPCR) 2007-05-15
US-2010303802-A1 Antibody directed to g protein coupled receptors (gpcr) 2007-05-15
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