Pyrene-dU-CE Phosphoramidite

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Pyrene-dU-CE Phosphoramidite

Pyrene-dU-CE Phosphoramidite | 199920-17-7

Catalog Number R10-0010
Category Phosphoramidite
Molecular Formula C57H55N4O8P
Molecular Weight 955.04
Catalog Number Size Price Quantity
R10-0010 -- $--

Product Introduction

Pyrene-dU-CE phosphoramidite, a key element in the creation of fluorescent oligonucleotides, boasts unique chemical properties that lend themselves to targeted detection of RNA or DNA sequences. Widely employed in both disease diagnosis and drug discovery, this highly potent compound serves as an engine of innovation in the ever-evolving field of molecular biology.

Chemical Information

Synonyms Pyrene phosphoramidite dU;5'-Dimethoxytrityl-5-(pyren-1-yl-ethynyl)-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Purity NMR 1H (95%), 31P, HPLC-MS
IUPAC Name 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-[2,4-dioxo-5-(2-pyren-1-ylethynyl)pyrimidin-1-yl]oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Canonical SMILES CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=C(C(=O)NC5=O)C#CC6=C7C=CC8=CC=CC9=C8C7=C(C=C9)C=C6
InChI InChI=1S/C57H55N4O8P/c1-37(2)61(38(3)4)70(67-33-11-32-58)69-50-34-52(60-35-43(55(62)59-56(60)63)21-17-39-16-18-42-20-19-40-12-10-13-41-22-31-49(39)54(42)53(40)41)68-51(50)36-66-57(44-14-8-7-9-15-44,45-23-27-47(64-5)28-24-45)46-25-29-48(65-6)30-26-46/h7-10,12-16,18-20,22-31,35,37-38,50-52H,11,33-34,36H2,1-6H3,(H,59,62,63)/t50-,51+,52+,70?/m0/s1
InChI Key UPMNDVODTLNHCL-UTNLAKSGSA-N
Solubility good in dichloromethane and acetonitrile
Appearance yellowish foam
  • Product Specification
ε, L⋅mol-1⋅cm-1 12600; 21900; 16000; 14200
Fluorescence Quantum Yield ~0.1
Excitation 260; 282; 365; 392
Emission 460
Storage Store at -20°C
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