5'-O-DMT-2'-deoxyinosine 3'-CE phosphoramidite

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5'-O-DMT-2'-deoxyinosine 3'-CE phosphoramidite

5'-O-DMT-2'-deoxyinosine 3'-CE phosphoramidite | 141684-35-7

Catalog Number R10-0007
Category DNA Stains
Molecular Formula C40H47N6O7P
Molecular Weight 754.83
Catalog Number Size Price Quantity
R10-0007 -- $--

Product Introduction

5'-O-DMT-2'-deoxyinosine 3'-CE phosphoramidite is a key reagent used in the biomedical industry for the synthesis of modified nucleosides. It is commonly employed in the development of DNA and RNA molecules for research purposes, such as studying DNA-protein interactions or designing gene therapies. Its unique chemical structure enables specific targeting and modulation of gene expression related to certain diseases, providing insights into novel treatment strategies.

Chemical Information

Synonyms Inosine (dI) phosphoramidite;2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite; DMT-dI Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxyinosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Purity ≥98% by HPLC
IUPAC Name 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Canonical SMILES CC(C)N(C(C)C)P(OCCC#N)OC1CC(OC1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C5N=CNC6=O
InChI InChI=1S/C40H47N6O7P/c1-27(2)46(28(3)4)54(51-22-10-21-41)53-34-23-36(45-26-44-37-38(45)42-25-43-39(37)47)52-35(34)24-50-40(29-11-8-7-9-12-29,30-13-17-32(48-5)18-14-30)31-15-19-33(49-6)20-16-31/h7-9,11-20,25-28,34-36H,10,22-24H2,1-6H3,(H,42,43,47)/t34-,35+,36+,54?/m0/s1
InChI Key ZKGZROFWRPJVEB-XZYUMQGLSA-N
Appearance White to off-white powder
Boiling Point 857.1±65.0°C (Predicted)
  • Product Specification
Storage Store at -20°C
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